NEURL2 anticorps (N-Term)

N° du produit ABIN2784965

Détail du produit anti-NEURL2 anticorps

Antigène: NEURL2 (Neuralized Homolog 2 (NEURL2))

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Cobaye, Boeuf (Vache), Chien, Cheval, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NEURL2 est non-conjugé

Application: Western Blotting (WB)

Séquence: MAAASEPVDS GALWGLERPE PPPTRFHRVH GANIRVDPSG TRATRVESFA

Homologie: Cow: 93%, Dog: 93%, Guinea Pig: 100%, Horse: 86%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against NEURL2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human NEURL2

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 285 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur NEURL2

Antigène: NEURL2 (Neuralized Homolog 2 (NEURL2))

Autre désignation: NEURL2 (NEURL2 Produits)

Synonymes: anticorps C20orf163, anticorps OZZ, anticorps OZZ-E3, anticorps Neur2, anticorps Ozz, anticorps Ozz-E3, anticorps neuralized E3 ubiquitin protein ligase 2, anticorps NEURL2, anticorps Neurl2

Sujet: NEURL2 contains 1 NHR (neuralized homology repeat) domain and 1 SOCS box domain. NEURL2 plays an important role in the process of myofiber differentiation and maturation. NEURL2 is the probable substrate-recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex, which mediates the ubiquitination of proteins. NEURL2 probably contributes to catalysis through recognition and positioning of the substrate and the ubiquitin-conjugating enzyme. During myogenesis, it controls the ubiquitination and degradation of the specific pool of CTNNB1/beta-catenin located at the sarcolemma.
Alias Symbols: C20orf163, MGC125934, MGC125935, OZZ, Ozz-E3
Protein Interaction Partner: CTNNB1,
Protein Size: 285

Poids moléculaire: 32 kDa

ID gène: 140825

NCBI Accession: NM_080749, NP_542787

UniProt: Q9BR09