MTPN anticorps (Middle Region)
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- Antigène Voir toutes MTPN Anticorps
- MTPN (Myotrophin (MTPN))
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Épitope
- Middle Region
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Reactivité
- Humain, Souris, Rat, Chien, Boeuf (Vache), Cobaye, Cheval, Lapin, Poisson zèbre (Danio rerio)
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp MTPN est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- GRKPLHYAAD CGQLEILEFL LLKGADINAP DKHHITPLLS AVYEGHVSCV
- Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%
- Attributs du produit
- This is a rabbit polyclonal antibody against MTPN. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the middle region of human MTPN
- Top Product
- Discover our top product MTPN Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 118 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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Sparing of the dystrophin-deficient cranial sartorius muscle is associated with classical and novel hypertrophy pathways in GRMD dogs." dans: The American journal of pathology, Vol. 183, Issue 5, pp. 1411-24, (2013) (PubMed).
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Sparing of the dystrophin-deficient cranial sartorius muscle is associated with classical and novel hypertrophy pathways in GRMD dogs." dans: The American journal of pathology, Vol. 183, Issue 5, pp. 1411-24, (2013) (PubMed).
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- Antigène
- MTPN (Myotrophin (MTPN))
- Autre désignation
- MTPN (MTPN Produits)
- Synonymes
- anticorps MGC76285, anticorps GCDP, anticorps V-1, anticorps Gcdp, anticorps wu:fa10f07, anticorps zgc:64078, anticorps 5033418D15Rik, anticorps V1, anticorps myotrophin, anticorps myotrophin S homeolog, anticorps mtpn, anticorps MTPN, anticorps Mtpn, anticorps mtpn.S
- Sujet
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MTPN has a potential role in cerebellar morphogenesis. MTPN may function in differentiation of cerebellar neurons, particularly of granule cells. MTPN seems to be associated with cardiac hypertrophy.The transcript produced from this gene is bi-cistronic and can encode both myotrophin and leucine zipper protein 6. The myotrophin protein is associated with cardiac hypertrophy, where it is involved in the conversion of NFkappa B p50-p65 heterodimers to p50-p50 and p65-p65 homodimers. This protein also has a potential function in cerebellar morphogenesis, and it may be involved in the differentiation of cerebellar neurons, particularly of granule cells. A cryptic ORF at the 3' end of this transcript uses a novel internal ribosome entry site and a non-AUG translation initiation codon to produce leucine zipper protein 6, a 6.4 kDa tumor antigen that is associated with myeloproliferative disease.
Alias Symbols: FLJ31098, GCDP, V-1
Protein Interaction Partner: RBBP4, RAB1A, PTPN11, OXCT1, MTAP, PDIA3, ATP6V1A, UBC, NPLOC4, ELAVL1, MAPK1, CAPZB, RELA, NFKB1, REL, DSTYK,
Protein Size: 118 - Poids moléculaire
- 13 kDa
- ID gène
- 136319
- NCBI Accession
- NM_145808, NP_665807
- UniProt
- P58546
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