GRPEL2 anticorps (Middle Region)

N° du produit ABIN2785166

Détail du produit anti-GRPEL2 anticorps

Antigène: GRPEL2 (GrpE-Like 2, Mitochondrial (GRPEL2))

Épitope: Middle Region

Reactivité: Humain, Souris, Rat, Lapin, Chien, Cobaye, Cheval, Boeuf (Vache), Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GRPEL2 est non-conjugé

Application: Western Blotting (WB)

Séquence: HEHELICHVP AGVGVQPGTV ALVRQDGYKL HGRTIRLARV EVAVESQRRL

Homologie: Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%

Attributs du produit: This is a rabbit polyclonal antibody against GRPEL2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human GRPEL2

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 225 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur GRPEL2

Antigène: GRPEL2 (GrpE-Like 2, Mitochondrial (GRPEL2))

Autre désignation: GRPEL2 (GRPEL2 Produits)

Synonymes: anticorps mt-GrpE2, anticorps mt-Grpel2, anticorps Afap1l1, anticorps Mt-GrpE2, anticorps GrpE-like 2, mitochondrial, anticorps GrpE like 2, mitochondrial, anticorps Grpel2, anticorps GRPEL2

Sujet: GRPEL2 is an essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. GRPEL2 seems to control the nucleotide-dependent binding of mitochondrial HSP70 to substrate proteins. GRPEL2 stimulates ATPase activity of mt-HSP70. GRPEL2 may also serve to modulate the interconversion of oligomeric (inactive) and monomeric (active) forms of mt-HSP70.
Alias Symbols: DKFZp451C205, FLJ23713, FLJ33918, Mt-GrpE#2
Protein Interaction Partner: ELAVL1, UBC, HSPA4,
Protein Size: 225

Poids moléculaire: 25 kDa

ID gène: 134266

NCBI Accession: NM_152407, NP_689620

UniProt: Q8TAA5