RDH12 anticorps (Middle Region)

N° du produit ABIN2785176

Détail du produit anti-RDH12 anticorps

Antigène: RDH12 (Retinol Dehydrogenase 12 (All-Trans/9-Cis/11-Cis) (RDH12))

Épitope: Middle Region

Reactivité: Humain, Porc, Rat, Chien, Boeuf (Vache), Cobaye, Lapin, Cheval, Saccharomyces cerevisiae, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RDH12 est non-conjugé

Application: Western Blotting (WB)

Séquence: AKRLQGTGVT TYAVHPGVVR SELVRHSSLL CLLWRLFSPF VKTAREGAQT

Homologie: Cow: 85%, Dog: 92%, Guinea Pig: 79%, Horse: 86%, Human: 100%, Pig: 86%, Rabbit: 85%, Rat: 79%, Yeast: 79%, Zebrafish: 92%

Attributs du produit: This is a rabbit polyclonal antibody against RDH12. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human RDH12

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 316 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur RDH12

Antigène: RDH12 (Retinol Dehydrogenase 12 (All-Trans/9-Cis/11-Cis) (RDH12))

Autre désignation: RDH12 (RDH12 Produits)

Sujet: RDH12 is an NADPH-dependent retinal reductase whose highest activity is toward 9-cis and all-trans-retinol. RDH12 also plays a role in the metabolism of short-chain aldehydes but does not exhibit steroid dehydrogenase activity. Defects in this gene are a cause of Leber congenital amaurosis type 3 (LCA3). The protein encoded by this gene is an NADPH-dependent retinal reductase whose highest activity is toward 9-cis and all-trans-retinol. The encoded enzyme also plays a role in the metabolism of short-chain aldehydes but does not exhibit steroid dehydrogenase activity. Defects in this gene are a cause of Leber congenital amaurosis type 3 (LCA3).
Alias Symbols: FLJ30273, LCA3, LCA13, SDR7C2
Protein Interaction Partner: RBPMS, UBC, ANXA8L1, MAP1LC3A, BUB1,
Protein Size: 316

Poids moléculaire: 35 kDa

ID gène: 145226

NCBI Accession: NM_152443, NP_689656

UniProt: Q96NR8