PDE12 anticorps (Middle Region)
-
- Antigène Voir toutes PDE12 Anticorps
- PDE12 (Phosphodiesterase 12 (PDE12))
-
Épitope
- Middle Region
-
Reactivité
- Humain, Souris, Rat, Boeuf (Vache), Cobaye, Cheval, Lapin, Chien
-
Hôte
- Lapin
-
Clonalité
- Polyclonal
-
Conjugué
- Cet anticorp PDE12 est non-conjugé
-
Application
- Western Blotting (WB)
- Séquence
- CLDYIFIDLN ALEVEQVIPL PSHEEVTTHQ ALPSVSHPSD HIALVCDLKW
- Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
- Attributs du produit
- This is a rabbit polyclonal antibody against 2'-PDE. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the middle region of human 2'-PDE
- Top Product
- Discover our top product PDE12 Anticorps primaire
-
-
- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
-
Antigen size: 609 AA
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
- Antigène
- PDE12 (Phosphodiesterase 12 (PDE12))
- Autre désignation
- PDE12 (PDE12 Produits)
- Synonymes
- anticorps 2'-PDE, anticorps E430028B21Rik, anticorps LRRGT00074, anticorps RGD1310975, anticorps phosphodiesterase 12 S homeolog, anticorps phosphodiesterase 12, anticorps pde12.S, anticorps PDE12, anticorps pde12, anticorps Pde12
- Sujet
-
2'-PDE is an enzyme that cleaves 2',5'-phosphodiester bond linking adenosines of the 5'-triphosphorylated oligoadenylates, triphosphorylated oligoadenylates referred as 2-5A modulates the 2-5A system. This enzyme degraded triphosphorylated 2-5A to produce AMP and ATP. 2'-PDE also cleaves 3',5'-phosphodiester bond of oligoadenylates. 2'-PDE play a role as a negative regulator of the 2-5A system that is one of the major pathways for antiviral and antitumor functions induced by interferons (IFNs). Suppression of this enzyme induces reduction of viral replication in Hela cells, thus counteracting the antiviral pathway probably by inhibiting the 2-5A system.
Alias Symbols: 2'-PDE
Protein Interaction Partner: SUMO2, SUMO1, UBC, NEDD8, DCTPP1, NPLOC4, UBQLN2, EHD1, WDR4, PDLIM5, SAE1, UBA2, CUL5, XPNPEP1, STAT6, RAD23B, PGGT1B, DNAJB1, ADSL, APEX2, COPS5, CUL3, UBL4A,
Protein Size: 609 - Poids moléculaire
- 67 kDa
- ID gène
- 201626
- NCBI Accession
- NM_177966, NP_808881
- UniProt
- Q6L8Q7
-