Ensa anticorps (N-Term)

N° du produit ABIN2785426

Détail du produit anti-Ensa anticorps

Antigène: Ensa (ENSA) (Endosulfine alpha (ENSA))

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Porc, Lapin, Boeuf (Vache), Chien, Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Ensa est non-conjugé

Application: Western Blotting (WB)

Séquence: MAGGLGCDVC YWFVEDTQEK EGILPERAEE AKLKAKYPSL GQKPGGSDFL

Homologie: Cow: 92%, Dog: 92%, Horse: 92%, Human: 100%, Mouse: 92%, Pig: 92%, Rabbit: 92%, Rat: 92%

Attributs du produit: This is a rabbit polyclonal antibody against ENSA. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human ENSA

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 113 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur Ensa

Antigène: Ensa (ENSA) (Endosulfine alpha (ENSA))

Autre désignation: ENSA (ENSA Produits)

Synonymes: anticorps ARPP-19e, anticorps 1700020C18Rik, anticorps 2610007F17Rik, anticorps AI451924, anticorps ensa, anticorps si:dkeyp-24a7.3, anticorps ensaa, anticorps endosulfine alpha, anticorps endosulfine alpha a, anticorps endosulfine alpha S homeolog, anticorps ENSA, anticorps Ensa, anticorps ensa, anticorps ensaa, anticorps ensa.S

Sujet: The protein encoded by this gene belongs to a highly conserved cAMP-regulated phosphoprotein (ARPP) family. This protein was identified as an endogenous ligand for the sulfonylurea receptor, ABCC8/SUR1. ABCC8 is the regulatory subunit of the ATP-sensitive potassium (KATP) channel, which is located on the plasma membrane of pancreatic beta cells and plays a key role in the control of insulin release from pancreatic beta cells. This protein is thought to be an endogenous regulator of KATP channels. In vitro studies have demonstrated that this protein modulates insulin secretion through the interaction with KATP channel, and this gene has been proposed as a candidate gene for type 2 diabetes. At least eight alternatively spliced transcript variants encoding distinct isoforms have been observed.
Alias Symbols: MGC4319, MGC78563, MGC8394, ARPP-19e
Protein Interaction Partner: UBC, SNCA, PSEN1, ACD, POT1, RAP2A, RIM15, KCTD15, ARIH2, ABCC8, ENO2, MCM3,
Protein Size: 113

Poids moléculaire: 12 kDa

ID gène: 2029

NCBI Accession: NM_207047, NP_996930

UniProt: O43768