STAMBP anticorps (N-Term)

N° du produit ABIN2785428

Détail du produit anti-STAMBP anticorps

Antigène: STAMBP (STAM Binding Protein (STAMBP))

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye, Cheval, Lapin, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp STAMBP est non-conjugé

Application: Western Blotting (WB)

Séquence: SDHGDVSLPP EDRVRALSQL GSAVEVNEDI PPRRYFRSGV EIIRMASIYS

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 100%, Zebrafish: 79%

Attributs du produit: This is a rabbit polyclonal antibody against STAMBP. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human STAMBP

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 424 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur STAMBP

Antigène: STAMBP (STAM Binding Protein (STAMBP))

Autre désignation: STAMBP (STAMBP Produits)

Synonymes: anticorps AMSH, anticorps 5330424L14Rik, anticorps 5730422L11Rik, anticorps AW107289, anticorps Amsh, anticorps mKIAA4198, anticorps stambp, anticorps zgc:66147, anticorps STAM binding protein, anticorps Stam binding protein, anticorps STAM binding protein a, anticorps STAMBP, anticorps Stambp, anticorps stambpa

Sujet: Cytokine-mediated signal transduction in the JAK-STAT cascade requires the involvement of adaptor molecules. One such signal-transducing adaptor molecule contains an SH3 domain that is required for induction of MYC and cell growth. STAMBP binds to the SH3 domain of the signal-transducing adaptor molecule, and plays a critical role in cytokine-mediated signaling for MYC induction and cell cycle progression. Cytokine-mediated signal transduction in the JAK-STAT cascade requires the involvement of adaptor molecules. One such signal-transducing adaptor molecule contains an SH3 domain that is required for induction of MYC and cell growth. The protein encoded by this gene binds to the SH3 domain of the signal-transducing adaptor molecule, and plays a critical role in cytokine-mediated signaling for MYC induction and cell cycle progression. Multiple alternatively spliced transcript variants encoding the same protein isoform have been found for this gene.
Alias Symbols: AMSH, MGC126516, MGC126518
Protein Interaction Partner: CHMP1B, CHMP3, GRB2, UBC, TNFRSF1A, GJA1, MAP3K2, VAMP8, SUMO1, NEDD8, CLTC, FDPS, STAM, STAM2, GRAP2, TRIP13, SPG7, CHMP1A, ITGA5, CYP2C9, NTPCR, CHMP5, SMAD7, SMAD6, PJA1, USP28, USP21, CHMP4B, AMN, CTNNBL1, UACA, CHMP4A, MAP2K5, ALAS1, CASR, UBE2S, TRA
Protein Size: 424

Poids moléculaire: 48 kDa

ID gène: 10617

NCBI Accession: NM_213622, NP_998787

UniProt: O95630