HSD17B3 anticorps (N-Term)

N° du produit ABIN2785439

Détail du produit anti-HSD17B3 anticorps

Antigène: HSD17B3 (Hydroxysteroid (17-Beta) Dehydrogenase 3 (HSD17B3))

Épitope: N-Term

Reactivité: Humain, Rat, Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HSD17B3 est non-conjugé

Application: Western Blotting (WB)

Séquence: AVITGAGDGI GKAYSFELAK RGLNVVLISR TLEKLEAIAT EIERTTGRSV

Homologie: Horse: 79%, Human: 100%, Rat: 91%

Attributs du produit: This is a rabbit polyclonal antibody against HSD17B3. It was validated on Western Blot.

Purification: Affinity Purified

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 310 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-HSD17B3 (ABIN2785439)

Bertin, Dury, Ouellet, Pelletier, Labrie: "Localization of the androgen-synthesizing enzymes, androgen receptor, and sex steroids in the vagina: possible implications for the treatment of postmenopausal sexual dysfunction." dans: The journal of sexual medicine, Vol. 11, Issue 8, pp. 1949-61, (2014) (PubMed).

Détails sur HSD17B3

Antigène: HSD17B3 (Hydroxysteroid (17-Beta) Dehydrogenase 3 (HSD17B3))

Autre désignation: HSD17B3 (HSD17B3 Produits)

Synonymes: anticorps EDH17B3, anticorps SDR12C2, anticorps hydroxysteroid (17-beta) dehydrogenase 3, anticorps hydroxysteroid 17-beta dehydrogenase 3, anticorps Hsd17b3, anticorps HSD17B3

Sujet: This isoform of 17 beta-hydroxysteroid dehydrogenase is expressed predominantly in the testis and catalyzes the conversion of androstenedione to testosterone. It preferentially uses NADP as cofactor. Deficiency can result in male pseudohermaphroditism with gynecomastia.
Alias Symbols: EDH17B3, SDR12C2
Protein Size: 310

Poids moléculaire: 34 kDa

ID gène: 3293

NCBI Accession: NM_000197, NP_000188

UniProt: P37058

Pathways: Metabolism of Steroid Hormones and Vitamin D, Steroid Hormone Biosynthesis