AP2B1 anticorps (C-Term)

N° du produit ABIN2785455

Détail du produit anti-AP2B1 anticorps

Antigène: AP2B1 (Adaptor-Related Protein Complex 2, beta 1 Subunit (AP2B1))

Épitope: C-Term

Reactivité: Humain, Souris, Rat, Chien, Boeuf (Vache), Lapin, Cobaye, Cheval, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp AP2B1 est non-conjugé

Application: Western Blotting (WB)

Séquence: GAVDLLGGGL DSLLGSDLGG GIGGSPAVGQ SFIPSSVPAT FAPSPTPAVV

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

Attributs du produit: This is a rabbit polyclonal antibody against AP2B1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human AP2B1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 951 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-AP2B1 (ABIN2785455)

Schmid, Ford, Burtey, Praefcke, Peak-Chew, Mills, Benmerah, McMahon: "Role of the AP2 beta-appendage hub in recruiting partners for clathrin-coated vesicle assembly." dans: PLoS biology, Vol. 4, Issue 9, pp. e262, (2006) (PubMed).

Détails sur AP2B1

Antigène: AP2B1 (Adaptor-Related Protein Complex 2, beta 1 Subunit (AP2B1))

Autre désignation: AP2B1 (AP2B1 Produits)

Synonymes: anticorps 5-HT(2B), anticorps 5-HT2B, anticorps ADTB2, anticorps AP105B, anticorps AP2-BETA, anticorps CLAPB1, anticorps 1300012O03Rik, anticorps AI788979, anticorps fa16e07, anticorps wu:fa16c06, anticorps wu:fa16e07, anticorps wu:fc18c08, anticorps zgc:55659, anticorps 5-hydroxytryptamine receptor 2B, anticorps adaptor related protein complex 2 beta 1 subunit, anticorps adaptor-related protein complex 2, beta 1 subunit, anticorps adaptor related protein complex 2 beta 1 subunit L homeolog, anticorps HTR2B, anticorps AP2B1, anticorps Ap2b1, anticorps ap2b1, anticorps ap2b1.L

Sujet: AP2B1 is one of two large chain components of the assembly protein complex 2, which serves to link clathrin to receptors in coated vesicles. AP2B1 is found on the cytoplasmic face of coated vesicles in the plasma membrane.The protein encoded by this gene is one of two large chain components of the assembly protein complex 2, which serves to link clathrin to receptors in coated vesicles. The encoded protein is found on the cytoplasmic face of coated vesicles in the plasma membrane. Two transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: ADTB2, AP105B, AP2-BETA, CLAPB1, DKFZp781K0743
Protein Interaction Partner: NEU4, XRCC6BP1, THAP1, U2AF1, KPNA2, SLC25A6, AFF4, TXN2, PIP5K1C, RAPGEF3, AP1M2, SUMO2, GTF2I, UBC, EGFR, SUMO1, NEDD8, EPHA2, RPA3, RPA2, RPA1, SEC24C, NUSAP1, EPN1, XPO7, PLOD2, LNPEP, GRB2, LDLRAP1, AP2M1, UBD, RNF11, MMS19, ITGA4, FN1, ERBB2, DAB2,
Protein Size: 951

Poids moléculaire: 105 kDa

ID gène: 163

NCBI Accession: NM_001030006, NP_001025177

UniProt: P63010

Pathways: EGFR Signaling Pathway, Neurotrophin Signaling Pathway, EGFR Downregulation