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Importin 5 anticorps (N-Term)

IPO5 Reactivité: Humain, Rat, Souris, Boeuf (Vache), Chien, Cobaye, Cheval, Lapin, Poisson zèbre (Danio rerio) WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2785469
  • Antigène Voir toutes Importin 5 (IPO5) Anticorps
    Importin 5 (IPO5)
    Épitope
    • 15
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivité
    Humain, Rat, Souris, Boeuf (Vache), Chien, Cobaye, Cheval, Lapin, Poisson zèbre (Danio rerio)
    Hôte
    • 37
    • 4
    Lapin
    Clonalité
    • 39
    • 2
    Polyclonal
    Conjugué
    • 13
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp Importin 5 est non-conjugé
    Application
    • 13
    • 13
    • 11
    • 7
    • 6
    • 5
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB)
    Séquence
    GNNQWPEGLK FLFDSVSSQN VGLREAALHI FWNFPGIFGN QQQHYLDVIK
    Homologie
    Cow: 93%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 93%, Zebrafish: 86%
    Attributs du produit
    This is a rabbit polyclonal antibody against RANBP5. It was validated on Western Blot.
    Purification
    Affinity Purified
    Immunogène
    The immunogen is a synthetic peptide directed towards the N terminal region of human RANBP5
    Top Product
    Discover our top product IPO5 Anticorps primaire
  • Indications d'application
    Optimal working dilutions should be determined experimentally by the investigator.
    Commentaires

    Antigen size: 1115 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Antigène
    Importin 5 (IPO5)
    Autre désignation
    RANBP5 (IPO5 Produits)
    Synonymes
    anticorps IPO5, anticorps RANBP5, anticorps IMB3, anticorps KPNB3, anticorps Pse1, anticorps imp5, anticorps 1110011C18Rik, anticorps 5730478E03Rik, anticorps AA409333, anticorps C76941, anticorps Kpnb3, anticorps Ranbp5, anticorps importin 5, anticorps IPO5, anticorps Ipo5
    Sujet
    Nucleocytoplasmic transport, a signal- and energy-dependent process, takes place through nuclear pore complexes embedded in the nuclear envelope. The import of proteins containing a nuclear localization signal (NLS) requires the NLS import receptor, a heterodimer of importin alpha and beta subunits also known as karyopherins. Importin alpha binds the NLS-containing cargo in the cytoplasm and importin beta docks the complex at the cytoplasmic side of the nuclear pore complex. In the presence of nucleoside triphosphates and the small GTP binding protein Ran, the complex moves into the nuclear pore complex and the importin subunits dissociate. Importin alpha enters the nucleoplasm with its passenger protein and importin beta remains at the pore. Interactions between importin beta and the FG repeats of nucleoporins are essential in translocation through the pore complex. The protein encoded by this gene is a member of the importin beta family.
    Alias Symbols: DKFZp686O1576, FLJ43041, IMB3, KPNB3, MGC2068, RANBP5, imp5
    Protein Interaction Partner: HUWE1, UBC, STAU1, ASB15, HK2, HEXB, ATIC, MCTS1, TNFAIP8, EZR, UBA1, TXNRD1, FBXO6, BHLHB9, EGFR, MUC1, SOX2, NPM1, HDAC2, LAS1L, PELP1, WASL, VCAM1, MAP1LC3A, ITGA4, FN1, CFTR, RPL7, CA9, NOTCH1, IPO4, TNPO1, KPNB1, RAN, CUL3, ACD, TINF2, TERF1, BKRF1,
    Protein Size: 1115
    Poids moléculaire
    125 kDa
    ID gène
    3843
    NCBI Accession
    NM_002271, NP_002262
    Pathways
    Protein targeting to Nucleus
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