JAK3 anticorps (N-Term)
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- Antigène Voir toutes JAK3 Anticorps
- JAK3 (Janus Kinase 3 (JAK3))
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Épitope
- N-Term
- Reactivité
- Humain, Souris, Rat, Boeuf (Vache), Chien, Cheval, Porc, Cobaye
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp JAK3 est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- APPSEETPLI PQRSCSLLST EAGALHVLLP ARGPGPPQRL SFSFGDHLAE
- Homologie
- Cow: 93%, Dog: 100%, Guinea Pig: 93%, Horse: 92%, Human: 100%, Mouse: 100%, Pig: 100%, Rat: 93%
- Attributs du produit
- This is a rabbit polyclonal antibody against JAK3. It was validated on Western Blot.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the N-terminal region of human JAK3
- Top Product
- Discover our top product JAK3 Anticorps primaire
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- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeat freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- JAK3 (Janus Kinase 3 (JAK3))
- Autre désignation
- JAK3 (JAK3 Produits)
- Synonymes
- anticorps JAK-3, anticorps JAK3_HUMAN, anticorps JAKL, anticorps L-JAK, anticorps LJAK, anticorps fae, anticorps wil, anticorps RATJAK3, anticorps JAK, anticorps Janus kinase 3, anticorps JAK3, anticorps Jak3
- Sujet
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The protein encoded by this gene is a member of the Janus kinase (JAK) family of tyrosine kinases involved in cytokine receptor-mediated intracellular signal transduction. It is predominantly expressed in immune cells and transduces a signal in response to its activation via tyrosine phosphorylation by interleukin receptors. Mutations in this gene are associated with autosomal SCID (severe combined immunodeficiency disease).
Alias Symbols: JAKL, LJAK, JAK-3, L-JAK, JAK3_HUMAN
Protein Size: 619 - Poids moléculaire
- 68 kDa
- ID gène
- 3718
- NCBI Accession
- NM_000215, NP_000206
- UniProt
- Q8N1E8
- Pathways
- Signalistation JAK/STAT, Signalisation RTK, Response to Growth Hormone Stimulus, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Protein targeting to Nucleus, Activated T Cell Proliferation, Unfolded Protein Response
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