ALAS1 anticorps (N-Term)

N° du produit ABIN2785663

Cet anticorps anti-ALAS1 Polyclonal Lapin (ABIN2785663) détecte spécifiquement ALAS1 dans WB. L’anticorps est réactif avec des échantillons de Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye, Cheval, Lapin, Mouton et Poisson zèbre (Danio rerio).

Aperçu rapide pour ALAS1 anticorps (N-Term) (ABIN2785663)

Antigène: ALAS1 (Aminolevulinate, delta-, Synthase 1 (ALAS1))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye, Cheval, Lapin, Mouton, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ALAS1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-ALAS1 anticorps

Épitope: N-Term

Séquence: ETSAGPSVVS VKTDGGDPSG LLKNFQDIMQ KQRPERVSHL LQDNLPKSVS

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Sheep: 93%, Zebrafish: 86%

Attributs du produit: This is a rabbit polyclonal antibody against ALAS1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human ALAS1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 640 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur ALAS1

Antigène: ALAS1 (Aminolevulinate, delta-, Synthase 1 (ALAS1))

Autre désignation: ALAS1

Sujet: Delta-aminolevulinate synthase (ALAS, EC 2.3.1.37) catalyzes the condensation of glycine with succinyl-CoA to form delta-aminolevulinic acid. This nuclear-encoded mitochondrial enzyme is the first and rate-limiting enzyme in the mammalian heme biosynthetic pathway. There are 2 tissue-specific isozymes: a housekeeping enzyme encoded by the ALAS1 gene and an erythroid tissue-specific enzyme encoded by ALAS2.
Alias Symbols: ALAS, ALAS3, ALASH, MIG4
Protein Interaction Partner: FAM127C, KLHL35, ZNF564, TEKT4, DUSP19, SNX20, MTFR2, LONRF1, ZMAT1, CDC73, TTC23, CERK, SH2D4A, EP400, C2orf42, GNL3L, CCHCR1, POLDIP2, ZFYVE26, USP20, TMSB10, ZNF175, WIPF1, UBC, TMSB4XP6, TMSB4XP2, TMSB4XP1, TMSB4X, TCEA2, PPL, BCL7A, ALAS1, PLAU, VHL,
Protein Size: 640

Poids moléculaire: 70 kDa

ID gène: 211

NCBI Accession: NM_000688, NP_000679

UniProt: P13196

Pathways: Regulation of Lipid Metabolism by PPARalpha