IMPDH2 anticorps (N-Term)
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- Antigène Voir toutes IMPDH2 Anticorps
- IMPDH2 (IMP (Inosine 5'-Monophosphate) Dehydrogenase 2 (IMPDH2))
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Épitope
- N-Term
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Reactivité
- Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye, Cheval, Lapin, Poisson zèbre (Danio rerio)
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp IMPDH2 est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Séquence
- MADYLISGGT SYVPDDGLTA QQLFNCGDGL TYNDFLILPG YIDFTADQVD
- Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%
- Attributs du produit
- This is a rabbit polyclonal antibody against IMPDH2. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the N terminal region of human IMPDH2
- Top Product
- Discover our top product IMPDH2 Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 514 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- IMPDH2 (IMP (Inosine 5'-Monophosphate) Dehydrogenase 2 (IMPDH2))
- Autre désignation
- IMPDH2 (IMPDH2 Produits)
- Synonymes
- anticorps imp2, anticorps impd2, anticorps impdh-ii, anticorps impdh2, anticorps IMPD2, anticorps IMPDH-II, anticorps IMPD 2, anticorps IMPDH 2, anticorps cb635, anticorps wu:fb64g02, anticorps wu:fc43f09, anticorps IMPD, anticorps inosine monophosphate dehydrogenase 2, anticorps IMP (inosine 5'-monophosphate) dehydrogenase 2, anticorps inosine 5'-phosphate dehydrogenase 2, anticorps IMPDH2, anticorps impdh2.S, anticorps impdh2, anticorps Impdh2
- Sujet
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IMPDH2 is the rate-limiting enzyme in the de novo guanine nucleotide biosynthesis. It is thus involved in maintaining cellular guanine deoxy- and ribonucleotide pools needed for DNA and RNA synthesis. It catalyzes the NAD-dependent oxidation of inosine-5'-monophosphate into xanthine-5'-monophosphate, which is then converted into guanosine-5'-monophosphate. IMPDH2 is up-regulated in some neoplasms, suggesting it may play a role in malignant transformation.
Alias Symbols: IMPD2, IMPDH-II
Protein Interaction Partner: RSG1, APIP, HUWE1, UBC, IMPDH2, CDK2, RPA1, RPA3, RPA2, PRKAR2A, IMPDH1, EIF2S3, PARK2, MAPK10, SOX2, NPM1, PEX14, FN1, RPLP0P6, RPS6, RPL15, FOLR1, FBXO6, GRB2, UBQLN4, PIAS4, COPS5, COPS6, CUL3, YWHAZ, FBXO25, SIRT7, HDAC5, MME, SUMO4, AKT1, IKBKE, ATG5
Protein Size: 514 - Poids moléculaire
- 56 kDa
- ID gène
- 3615
- NCBI Accession
- NM_000884, NP_000875
- UniProt
- P12268
- Pathways
- Ribonucleoside Biosynthetic Process, SARS-CoV-2 Protein Interactome
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