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GALE anticorps (Middle Region)

GALE Reactivité: Humain, Rat, Chien, Porc, Lapin, Boeuf (Vache), Cheval WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2785691
  • Antigène Voir toutes GALE Anticorps
    GALE (UDP-Galactose-4-Epimerase (GALE))
    Épitope
    • 15
    • 8
    • 7
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reactivité
    • 35
    • 20
    • 6
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Humain, Rat, Chien, Porc, Lapin, Boeuf (Vache), Cheval
    Hôte
    • 46
    • 4
    Lapin
    Clonalité
    • 48
    • 2
    Polyclonal
    Conjugué
    • 21
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp GALE est non-conjugé
    Application
    • 39
    • 15
    • 13
    • 13
    • 5
    • 5
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Séquence
    PQGIPNNLMP YVSQVAIGRR EALNVFGNDY DTEDGTGVRD YIHVVDLAKG
    Homologie
    Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Pig: 100%, Rabbit: 100%, Rat: 93%
    Attributs du produit
    This is a rabbit polyclonal antibody against GALE. It was validated on Western Blot.
    Purification
    Affinity Purified
    Immunogène
    The immunogen is a synthetic peptide directed towards the middle region of human GALE
    Top Product
    Discover our top product GALE Anticorps primaire
  • Indications d'application
    Optimal working dilutions should be determined experimentally by the investigator.
    Commentaires

    Antigen size: 348 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Antigène
    GALE (UDP-Galactose-4-Epimerase (GALE))
    Autre désignation
    GALE (GALE Produits)
    Synonymes
    anticorps GALE, anticorps im:7147391, anticorps wu:fb05f01, anticorps zgc:136578, anticorps F15H21.11, anticorps F15H21_11, anticorps REB1, anticorps ROOT EPIDERMAL BULGER1, anticorps ROOT HAIR DEFECTIVE 1, anticorps UDP-GLUCOSE 4-EPIMERASE, anticorps UGE4, anticorps ECK0748, anticorps galD, anticorps JW0742, anticorps SMU.888, anticorps BA5505, anticorps BA5700, anticorps VFA0352, anticorps galE, anticorps 2310002A12Rik, anticorps AI323962, anticorps 1n569, anticorps xgale, anticorps SDR1E1, anticorps UDP-galactose-4-epimerase, anticorps NAD(P)-binding Rossmann-fold superfamily protein, anticorps UDP-galactose 4-epimerase GalE, anticorps UDP-glucose 4-epimerase, anticorps UDP-glucose 4-epimerase GalE, anticorps UDP-glucose/UDP-N-acetylglucosamine 4-epimerase, anticorps galactose-4-epimerase, UDP, anticorps UDP-galactose-4-epimerase L homeolog, anticorps GALE, anticorps gale, anticorps RHD1, anticorps ECs0787, anticorps galE, anticorps galE1, anticorps galE2, anticorps STY0809, anticorps galE-2, anticorps SG0897, anticorps galD, anticorps Ent638_1250, anticorps Gale, anticorps gale.L
    Sujet
    GALE is an UDP-galactose-4-epimerase which catalyzes two distinct but analogous reactions: the epimerization of UDP-glucose to UDP-galactose, and the epimerization of UDP-N-acetylglucosamine to UDP-N-acetylgalactosamine. The bifunctional nature of the enzyme has the important metabolic consequence that mutant cells (or individuals) are dependent not only on exogenous galactose, but also on exogenous N-acetylgalactosamine as a necessary precursor for the synthesis of glycoproteins and glycolipids. Mutations in this gene result in epimerase-deficiency galactosemia, also referred to as galactosemia type 3, a disease characterized by liver damage, early-onset cataracts, deafness and mental retardation, with symptoms ranging from mild ('peripheral' form) to severe ('generalized' form).
    Alias Symbols: SDR1E1
    Protein Interaction Partner: GALE, SUMO2, UBC, BAG3, FN1, APP,
    Protein Size: 348
    Poids moléculaire
    38 kDa
    ID gène
    2582
    NCBI Accession
    NM_001008216, NP_001008217
    UniProt
    Q14376
    Pathways
    Response to Water Deprivation, Cellular Glucan Metabolic Process
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