NLRP1 anticorps (N-Term)

N° du produit ABIN2785731

Détail du produit anti-NLRP1 anticorps

Antigène: NLRP1 (NLR Family, Pyrin Domain Containing 1 (NLRP1))

Épitope: N-Term

Reactivité: Humain, Souris, Boeuf (Vache), Chien, Cheval, Rat, Cobaye, Porc, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NLRP1 est non-conjugé

Application: Western Blotting (WB)

Séquence: DTQEPRIVIL QGAAGIGKST LARQVKEAWG RGQLYGDRFQ HVFYFSCREL

Homologie: Cow: 85%, Dog: 86%, Guinea Pig: 85%, Horse: 85%, Human: 100%, Mouse: 93%, Pig: 86%, Rabbit: 85%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against NLRP1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human NLRP1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 1375 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur NLRP1

Antigène: NLRP1 (NLR Family, Pyrin Domain Containing 1 (NLRP1))

Autre désignation: NLRP1 (NLRP1 Produits)

Sujet: This gene encodes a member of the Ced-4 family of apoptosis proteins. Ced-family members contain a caspase recruitment domain (CARD) and are known to be key mediators of programmed cell death. The encoded protein contains a distinct N-terminal pyrin-like
Alias Symbols: CARD7, CLR17.1, DEFCAP, DEFCAP-L/S, DKFZp586O1822, KIAA0926, NAC, NALP1, PP1044, SLEV1, VAMAS1
Protein Interaction Partner: TRIM68, CUL3, APOA1, NLRP1, PYCARD, NOD1, CASP5, CASP9, APAF1, CASP2, BCL2L1, BCL2, CASP1, NLRC4,
Protein Size: 1375

Poids moléculaire: 155 kDa

ID gène: 22861

NCBI Accession: NM_001033053, NP_001028225

UniProt: Q9C000

Pathways: Positive Regulation of Endopeptidase Activity, Inflammasome