Galectin 3 anticorps (N-Term)
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- Antigène Voir toutes Galectin 3 (LGALS3) Anticorps
- Galectin 3 (LGALS3)
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Épitope
- N-Term
- Reactivité
- Humain, Souris, Rat, Lapin, Porc, Chien, Cobaye, Cheval, Boeuf (Vache)
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp Galectin 3 est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Séquence
- GASYPGAYPG QAPPGAYPGQ APPGAYPGAP GAYPGAPAPG VYPGPPSGPG
- Homologie
- Cow: 93%, Dog: 93%, Guinea Pig: 92%, Horse: 92%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 92%, Rat: 93%
- Attributs du produit
- This is a rabbit polyclonal antibody against LGALS3. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the N terminal region of human LGALS3
- Top Product
- Discover our top product LGALS3 Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 250 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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Nicotine promotes apoptosis resistance of breast cancer cells and enrichment of side population cells with cancer stem cell-like properties via a signaling cascade involving galectin-3, α9 nicotinic ..." dans: Breast cancer research and treatment, Vol. 145, Issue 1, pp. 5-22, (2014) (PubMed).
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Nicotine promotes apoptosis resistance of breast cancer cells and enrichment of side population cells with cancer stem cell-like properties via a signaling cascade involving galectin-3, α9 nicotinic ..." dans: Breast cancer research and treatment, Vol. 145, Issue 1, pp. 5-22, (2014) (PubMed).
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- Antigène
- Galectin 3 (LGALS3)
- Autre désignation
- LGALS3 (LGALS3 Produits)
- Synonymes
- anticorps CBP 35, anticorps Gal-3, anticorps Galectin-3, anticorps leg3, anticorps galactoside-binding, anticorps galectin-3, anticorps lectin, anticorps soluble, anticorps CBP35, anticorps GAL3, anticorps GALBP, anticorps GALIG, anticorps L31, anticorps LGALS2, anticorps MAC2, anticorps MGC52947, anticorps MGC75803, anticorps LGALS3, anticorps gal-3, anticorps GBP, anticorps L-34, anticorps Mac-2, anticorps gal3, anticorps galectin 3, anticorps Galectin-3, anticorps avian beta-defensin 3, anticorps lectin, galactoside-binding, soluble, 3 L homeolog, anticorps lectin, galactoside-binding, soluble, 3, anticorps galectin 2, anticorps lectin, galactose binding, soluble 3, anticorps LGALS3, anticorps leg3, anticorps AvBD3, anticorps lgals3.L, anticorps lgals3, anticorps LGALS2, anticorps Lgals3
- Classe de substances
- Chemical
- Sujet
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LGALS3 is a galactose-specific lectin which binds IgE. IT may mediate with the alpha-3, beta-1 integrin the stimulation by CSPG4 of endothelial cells migration. Together with DMBT1, it is required for terminal differentiation of columnar epithelial cells during early embryogenesis.
Alias Symbols: CBP35, GAL3, GALBP, GALIG, LGALS2, MAC2, L31
Protein Interaction Partner: PRR13, SS18L1, PPIG, LGALS3, GOLGA2, MAP1LC3A, SQSTM1, RAB7A, LAMP1, EGFR, CFTR, PAXIP1, BARD1, AGPS, IGBP1, GTF2I, CLNS1A, APP, SLC25A5, ACTA1, MYOC, LGALS3BP, CYHR1, GEMIN4, SUFU, CUBN, CSNK1A1, LIM2, FCGR2A, ELN, MMP2, CSNK2A2, CSNK2A1, C1GALT1C1, LGAL
Protein Size: 250 - Poids moléculaire
- 26 kDa
- ID gène
- 3958
- NCBI Accession
- NM_002306, NP_002297
- UniProt
- P17931
- Pathways
- Signalisation RTK
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