ICA1 anticorps (N-Term)

N° du produit ABIN2785861

Détail du produit anti-ICA1 anticorps

Antigène: ICA1 (Islet Cell Autoantigen 1, 69kDa (ICA1))

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Chien, Cobaye, Cheval, Boeuf (Vache), Lapin, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ICA1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: SKAIVLYQKR ICFLSQEENE LGKFLRSQGF QDKTRAGKMM QATGKALCFS

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%

Attributs du produit: This is a rabbit polyclonal antibody against ICA1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human ICA1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 483 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-ICA1 (ABIN2785861)

Ewing, Chu, Elisma, Li, Taylor, Climie, McBroom-Cerajewski, Robinson, OConnor, Li, Taylor, Dharsee, Ho, Heilbut, Moore, Zhang, Ornatsky, Bukhman, Ethier, Sheng, Vasilescu, Abu-Farha, Lambert, Duewel et al.: "Large-scale mapping of human protein-protein interactions by mass spectrometry. ..." dans: Molecular systems biology, Vol. 3, pp. 89, (2007) (PubMed).

Détails sur ICA1

Antigène: ICA1 (Islet Cell Autoantigen 1, 69kDa (ICA1))

Autre désignation: ICA1 (ICA1 Produits)

Synonymes: anticorps ica1, anticorps MGC52730, anticorps ICA1, anticorps DKFZp469G0321, anticorps zgc:92566, anticorps 69kDa, anticorps ICA69, anticorps Ica69, anticorps MGC83241, anticorps ICAp69, anticorps islet cell autoantigen 1 L homeolog, anticorps islet cell autoantigen 1, anticorps Islet cell autoantigen 1, anticorps islet cell autoantigen 1 S homeolog, anticorps ica1.L, anticorps ICA1, anticorps ica1, anticorps ica69, anticorps Ica1, anticorps ica1.S

Sujet: ICA1 is a protein with an arfaptin homology domain that is found both in the cytosol and as membrane-bound form on the Golgi complex and immature secretory granules. This protein is believed to be an autoantigen in insulin-dependent diabetes mellitus and primary Sjogren's syndrome. This gene encodes a protein with an arfaptin homology domain that is found both in the cytosol and as membrane-bound form on the Golgi complex and immature secretory granules. This protein is believed to be an autoantigen in insulin-dependent diabetes mellitus and primary Sjogren's syndrome. Alternatively spliced variants which encode different protein isoforms have been described, however, not all variants have been fully characterized.
Alias Symbols: ICA69, ICAp69
Protein Interaction Partner: RAB2B, ING5, MBD3, CCDC28A, RAB2A, tbc-8, EXOC5, STK16, MKKS, KRT33B, CNTF,
Protein Size: 483

Poids moléculaire: 55 kDa

ID gène: 3382

NCBI Accession: NM_004968, NP_004959

UniProt: Q05084