GRF2 anticorps (C-Term)

N° du produit ABIN2785868

Détail du produit anti-GRF2 anticorps

Antigène: GRF2 (RAPGEF1) (Rap Guanine Nucleotide Exchange Factor (GEF) 1 (RAPGEF1))

Épitope: C-Term

Reactivité: Humain, Souris, Rat, Chien, Boeuf (Vache), Cobaye, Cheval, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GRF2 est non-conjugé

Application: Western Blotting (WB)

Séquence: LWAKEQNEEK SPNLTQFTEH FNNMSYWVRS IIMLQEKAQD RERLLLKFIK

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 100%

Attributs du produit: This is a rabbit polyclonal antibody against RAPGEF1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human RAPGEF1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 1077 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur GRF2

Antigène: GRF2 (RAPGEF1) (Rap Guanine Nucleotide Exchange Factor (GEF) 1 (RAPGEF1))

Autre désignation: RAPGEF1 (RAPGEF1 Produits)

Synonymes: anticorps C3G, anticorps GRF2, anticorps Link-GEFII, anticorps 4932418O06Rik, anticorps Grf2, anticorps RAPGEF1, anticorps C3G-1, anticorps C3G-2, anticorps C3g, anticorps rapgef1, anticorps zgc:56372, anticorps Rap guanine nucleotide exchange factor 1, anticorps Rap guanine nucleotide exchange factor like 1, anticorps Rap guanine nucleotide exchange factor (GEF) 1, anticorps Rap guanine nucleotide exchange factor 1 S homeolog, anticorps Rap guanine nucleotide exchange factor (GEF) 1b, anticorps RAPGEF1, anticorps RAPGEFL1, anticorps Rapgef1, anticorps rapgef1.S, anticorps rapgef1, anticorps rapgef1b, anticorps Rapgefl1

Sujet: RAPGEF1 is a human guanine nucleotide exchange factor. It transduces signals from CRK by binding the SH3 domain of CRK, and activating several members of the Ras family of GTPases. This signaling cascade protein may be involved in apoptosis, integrin-mediated signal transduction, and cell transformation.This gene encodes a human guanine nucleotide exchange factor. It transduces signals from CRK by binding the SH3 domain of CRK, and activating several members of the Ras family of GTPases. This signaling cascade that may be involved in apoptosis, integrin-mediated signal transduction, and cell transformation. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some variants has not been determined.
Alias Symbols: C3G, DKFZp781P1719, GRF2
Protein Interaction Partner: UBC, MBIP, SLC20A1, ATXN1, RPS15, CRKL, CRK, CBL, GRB2, NEDD9, RHOQ, BCAR1, SHC1, RRAS2, HRAS, RAP1B, HCK, RAP1A,
Protein Size: 1077

Poids moléculaire: 120 kDa

ID gène: 2889

NCBI Accession: NM_005312, NP_005303

UniProt: Q13905

Pathways: Interferon-gamma Pathway, Neurotrophin Signaling Pathway, Platelet-derived growth Factor Receptor Signaling, Signaling of Hepatocyte Growth Factor Receptor