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INPP5B anticorps (Middle Region)

INPP5B Reactivité: Humain, Souris, Rat, Chien, Lapin, Cheval, Cobaye WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2785875
  • Antigène Voir toutes INPP5B Anticorps
    INPP5B (Inositol Polyphosphate-5-Phosphatase, 75kDa (INPP5B))
    Épitope
    • 9
    • 8
    • 7
    • 5
    • 4
    • 1
    • 1
    Middle Region
    Reactivité
    Humain, Souris, Rat, Chien, Lapin, Cheval, Cobaye
    Hôte
    • 34
    • 2
    Lapin
    Clonalité
    • 36
    Polyclonal
    Conjugué
    • 15
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp INPP5B est non-conjugé
    Application
    • 23
    • 18
    • 17
    • 14
    • 5
    • 2
    • 1
    Western Blotting (WB)
    Séquence
    IHNGQVPCHF EFINKPDEES YCKQWLNANP SRGFLLPDSD VEIDLELFVN
    Homologie
    Dog: 85%, Guinea Pig: 92%, Horse: 92%, Human: 100%, Mouse: 92%, Rabbit: 77%, Rat: 92%
    Attributs du produit
    This is a rabbit polyclonal antibody against INPP5B. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogène
    The immunogen is a synthetic peptide directed towards the middle region of human INPP5B
    Top Product
    Discover our top product INPP5B Anticorps primaire
  • Indications d'application
    Optimal working dilutions should be determined experimentally by the investigator.
    Commentaires

    Antigen size: 913 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Tothova, Kollipara, Huntly, Lee, Castrillon, Cullen, McDowell, Lazo-Kallanian, Williams, Sears, Armstrong, Passegué, DePinho, Gilliland: "FoxOs are critical mediators of hematopoietic stem cell resistance to physiologic oxidative stress." dans: Cell, Vol. 128, Issue 2, pp. 325-39, (2007) (PubMed).

  • Antigène
    INPP5B (Inositol Polyphosphate-5-Phosphatase, 75kDa (INPP5B))
    Autre désignation
    INPP5B (INPP5B Produits)
    Synonymes
    anticorps 75kDa, anticorps AW260155, anticorps INPP5P, anticorps 5PTase, anticorps inositol polyphosphate-5-phosphatase B, anticorps type II inositol 1,4,5-trisphosphate 5-phosphatase-like, anticorps inositol polyphosphate-5-phosphatase B L homeolog, anticorps inositol polyphosphate 5-phosphatase OCRL-1, anticorps INPP5B, anticorps LOC100224437, anticorps inpp5b.L, anticorps LOC100159919, anticorps Inpp5b
    Sujet
    Cellular calcium signaling is controlled by the production of inositol phosphates (IPs) by phospholipase C in response to extracellular signals. The IP signaling molecules are inactivated by a family of inositol polyphosphate-5-phosphatases (5-phosphatases). INPP5B is the type II 5-phosphatase. The protein is localized to the cytosol and mitochondria, and associates with membranes through an isoprenyl modification near the C-terminus.Cellular calcium signaling is controlled by the production of inositol phosphates (IPs) by phospholipase C in response to extracellular signals. The IP signaling molecules are inactivated by a family of inositol polyphosphate-5-phosphatases (5-phosphatases). This gene encodes the type II 5-phosphatase. The protein is localized to the cytosol and mitochondria, and associates with membranes through an isoprenyl modification near the C-terminus. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.
    Alias Symbols: 5PTase, MGC65156, MGC71303
    Protein Interaction Partner: UBC, APP, SMURF1,
    Protein Size: 913
    Poids moléculaire
    77 kDa
    ID gène
    3633
    NCBI Accession
    NM_005540, NP_005531
    UniProt
    P32019
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