Lactate Dehydrogenase A anticorps (Middle Region)

N° du produit ABIN2785876

Détail du produit anti-Lactate Dehydrogenase A anticorps

Antigène: Lactate Dehydrogenase A (LDHA)

Épitope: Middle Region

Reactivité: Humain, Souris, Rat, Lapin, Boeuf (Vache), Cheval, Cobaye, Chien, Chévre, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Lactate Dehydrogenase A est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: PLSCHGWVLG EHGDSSVPVW SGMNVAGVSL KTLHPDLGTD KDKEQWKEVH

Homologie: Cow: 79%, Dog: 86%, Goat: 79%, Guinea Pig: 79%, Horse: 79%, Human: 100%, Mouse: 86%, Rabbit: 86%, Rat: 79%, Zebrafish: 92%

Attributs du produit: This is a rabbit polyclonal antibody against LDHA. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human LDHA

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 332 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-Lactate Dehydrogenase A (ABIN2785876)

Listerman, Bledau, Grishina, Neugebauer: "Extragenic accumulation of RNA polymerase II enhances transcription by RNA polymerase III." dans: PLoS genetics, Vol. 3, Issue 11, pp. e212, (2008) (PubMed).

Détails sur Lactate Dehydrogenase A

Antigène: Lactate Dehydrogenase A (LDHA)

Autre désignation: LDHA (LDHA Produits)

Synonymes: anticorps GSD11, anticorps LDH1, anticorps LDHM, anticorps LDH-M, anticorps ldh-h, anticorps ldha, anticorps ldha-B, anticorps ldhbb, anticorps trg-5, anticorps Ldh1, anticorps Ldhm, anticorps l7R2, anticorps gsd11, anticorps ldh-m, anticorps ldh1, anticorps ldhm, anticorps pig19, anticorps ldha1, anticorps ldhab, anticorps LDH-A, anticorps LDHC, anticorps lactate dehydrogenase A, anticorps lactate dehydrogenase B L homeolog, anticorps lactate dehydrogenase A4, anticorps lactate dehydrogenase A L homeolog, anticorps L-lactate dehydrogenase A chain, anticorps LDHA, anticorps ldhb.L, anticorps Ldha, anticorps ldha, anticorps ldha.L, anticorps LOC100713875

Sujet: LDHA catalyzes the conversion of L-lactate and NAD to pyruvate and NADH in the final step of anaerobic glycolysis. The protein is found predominantly in muscle tissue and belongs to the lactate dehydrogenase family. Mutations in this gene have been linked to exertional myoglobinuria.The protein encoded by this gene catalyzes the conversion of L-lactate and NAD to pyruvate and NADH in the final step of anaerobic glycolysis. The protein is found predominantly in muscle tissue and belongs to the lactate dehydrogenase family. Mutations in this gene have been linked to exertional myoglobinuria. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: LDH-M, LDH1, PIG19, LDHM, GSD11
Protein Interaction Partner: MAPK10, LDHB, FUS, HUWE1, ISG15, UBC, SUMO2, SUMO3, STAU1, RPA3, RPA2, RPA1, ASB9, RNF2, CNDP2, NAGK, C11orf58, NDRG1, BZW1, KYNU, TCEA1, SORD, SMS, RPS6KA1, PGD, PAFAH1B3, GSR, PDIA3, GNAI3, DLD, CSE1L, LDHAL6B, FTO, BCCIP, XRN1, FBXO6, UPF2, YWHAQ, METT
Protein Size: 332

Poids moléculaire: 37 kDa

ID gène: 3939

NCBI Accession: NM_005566, NP_005557

UniProt: P00338

Pathways: L'effet Warburg