14-3-3 sigma/SFN anticorps (Middle Region)
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- Antigène Voir toutes 14-3-3 sigma/SFN (SFN) Anticorps
- 14-3-3 sigma/SFN (SFN) (Stratifin (SFN))
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Épitope
- Middle Region
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Reactivité
- Humain, Souris, Rat, Chien, Boeuf (Vache), Cheval, Lapin, Mouton, Cobaye, Saccharomyces cerevisiae, Poisson zèbre (Danio rerio)
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp 14-3-3 sigma/SFN est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Séquence
- FHYEIANSPE EAISLAKTTF DEAMADLHTL SEDSYKDSTL IMQLLRDNLT
- Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Yeast: 93%, Zebrafish: 86%
- Attributs du produit
- This is a rabbit polyclonal antibody against SFN. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the middle region of human SFN
- Top Product
- Discover our top product SFN Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 248 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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Nicotinamide N-methyl transferase (NNMT) gene polymorphisms and risk for spina bifida." dans: Birth defects research. Part A, Clinical and molecular teratology, Vol. 82, Issue 10, pp. 670-5, (2008) (PubMed).
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Nicotinamide N-methyl transferase (NNMT) gene polymorphisms and risk for spina bifida." dans: Birth defects research. Part A, Clinical and molecular teratology, Vol. 82, Issue 10, pp. 670-5, (2008) (PubMed).
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- Antigène
- 14-3-3 sigma/SFN (SFN) (Stratifin (SFN))
- Autre désignation
- SFN (SFN Produits)
- Synonymes
- anticorps YWHAS, anticorps Er, anticorps Mme1, anticorps Ywhas, anticorps stratifin, anticorps SFN, anticorps Sfn
- Sujet
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SFN is an adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathway. SFN binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. When bound to KRT17, SFN regulates protein synthesis and epithelial cell growth by stimulating Akt/mTOR pathway.
Alias Symbols: YWHAS
Protein Interaction Partner: FAM9B, RAB3IP, LONRF1, CCDC102B, ZC2HC1C, DTL, FAM53C, MKRN3, FOXO4, MAGEA1, CCNH, SIK3, ZFYVE19, YWHAZ, VCL, UBE2V1, SNRPF, UBE2R2, PAK2, G6PD, TARDBP, EGFR, BAD, MARK3, HDAC7, HDAC5, HDAC4, RAF1, CDC25C, MST1R, ABL1, HNRNPD, ATF2, TRIM32, COPS6, UBC, TP
Protein Size: 248 - Poids moléculaire
- 28 kDa
- ID gène
- 2810
- NCBI Accession
- NM_006142, NP_006133
- UniProt
- P31947
- Pathways
- Signalisation p53, Myometrial Relaxation and Contraction
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