Ubiquilin 1 anticorps (Middle Region)
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- Antigène Voir toutes Ubiquilin 1 (UBQLN1) Anticorps
- Ubiquilin 1 (UBQLN1)
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Épitope
- Middle Region
- Reactivité
- Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye, Cheval, Lapin, Mouton, Poisson zèbre (Danio rerio)
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp Ubiquilin 1 est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Séquence
- QFGGNPFASL VSNTSSGEGS QPSRTENRDP LPNPWAPQTS QSSSASSGTA
- Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 92%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 79%
- Attributs du produit
- This is a rabbit polyclonal antibody against UBQLN1. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the middle region of human UBQLN1
- Top Product
- Discover our top product UBQLN1 Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 589 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- Ubiquilin 1 (UBQLN1)
- Autre désignation
- UBQLN1 (UBQLN1 Produits)
- Synonymes
- anticorps UBQLN1, anticorps DA41, anticorps DSK2, anticorps PLIC-1, anticorps UBQN, anticorps XDRP1, anticorps 1110046H03Rik, anticorps 1810030E05Rik, anticorps AU019746, anticorps C77538, anticorps D13Ertd372e, anticorps Da41, anticorps Dsk2, anticorps Plic-1, anticorps Plic1, anticorps Xdrp1, anticorps ubiquilin 1, anticorps UBQLN1, anticorps Ubqln1
- Sujet
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UBQLN1 is an ubiquitin-like protein (ubiquilin) that shares a high degree of similarity with related products in yeast, rat and frog. Ubiquilins contain an N-terminal ubiquitin-like domain and a C-terminal ubiquitin-associated domain. They physically associate with both proteasomes and ubiquitin ligases, and thus are thought to functionally link the ubiquitination machinery to the proteasome to affect in vivo protein degradation. This ubiquilin has also been shown to modulate accumulation of presenilin proteins, and it is found in lesions associated with Alzheimer's and Parkinson's disease. Two transcript variants encoding different isoforms have been found for this gene.This gene encodes an ubiquitin-like protein (ubiquilin) that shares high degree of similarity with related products in yeast, rat and frog. Ubiquilins contain a N-terminal ubiquitin-like domain and a C-terminal ubiquitin-associated domain. They physically associate with both proteasomes and ubiquitin ligases, and thus are thought to functionally link the ubiquitination machinery to the proteasome to affect in vivo protein degradation. This ubiquilin has also been shown to modulate accumulation of presenilin proteins, and is found in lesions associated with Alzheimer's and Parkinson's disease. Two transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: DA41, DSK2, FLJ90054, PLIC-1, XDRP1, UBQN
Protein Interaction Partner: MLLT6, MCM7, IL6ST, IGLC1, IGL, SLC29A2, HK2, GYPB, GRM2, GPX3, GABRD, FN1, FKBP2, FCGR2A, DEFA6, CTAG1B, CSTF2, COL10A1, COL1A2, CALU, IGLV2-14, FAM127B, CSTF2T, FAM127C, TMEM31, AGR3, ITPRIPL1, TRIM32, ACOT7, PLA2G16, SMR3B, AGR2, PSMD6, NUPL1, IST1, LI
Protein Size: 589 - Poids moléculaire
- 62 kDa
- ID gène
- 29979
- NCBI Accession
- NM_013438, NP_038466
- UniProt
- Q5T6J9
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