ORC6 anticorps (C-Term)
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- Antigène Voir toutes ORC6 Anticorps
- ORC6 (Origin Recognition Complex, Subunit 6 (ORC6))
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Épitope
- C-Term
- Reactivité
- Humain, Souris, Rat, Chien, Lapin, Boeuf (Vache), Cheval, Cobaye
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp ORC6 est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- VEAPAKEMEK VEEMPHKPQK DEDLTQDYEE WKRKILENAA SAQKATAE
- Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 86%
- Attributs du produit
- This is a rabbit polyclonal antibody against ORC6L. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the C terminal region of human ORC6L
- Top Product
- Discover our top product ORC6 Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 252 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- ORC6 (Origin Recognition Complex, Subunit 6 (ORC6))
- Autre désignation
- ORC6L (ORC6 Produits)
- Synonymes
- anticorps Orc6l, anticorps CG1584, anticorps DmORC 6, anticorps DmORC6, anticorps Dmel\\CG1584, anticorps ORC, anticorps ORC6, anticorps orc6, anticorps rDmORC, anticorps ORC6L, anticorps ARABIDOPSIS THALIANA ORIGIN RECOGNITION COMPLEX PROTEIN 6, anticorps ATORC6, anticorps ORIGIN RECOGNITION COMPLEX SUBUNIT 6, anticorps T2P11.3, anticorps T2P11_3, anticorps origin recognition complex protein 6, anticorps DDBDRAFT_0186183, anticorps DDBDRAFT_0233113, anticorps DDB_0186183, anticorps DDB_0233113, anticorps LOC100284755, anticorps orc6l, anticorps 6720420I10Rik, anticorps origin recognition complex, subunit 6, anticorps Origin recognition complex subunit 6, anticorps origin recognition complex subunit 6, anticorps origin recognition complex protein 6, anticorps origin recognition complex subunit Orc6, anticorps Orc6, anticorps ORC6, anticorps CpipJ_CPIJ005016, anticorps SJAG_01267, anticorps orcF, anticorps LOC100284755, anticorps orc6
- Sujet
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The origin recognition complex (ORC) is a highly conserved six subunit protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. ORC6L is a subunit of the ORC complex. It has been shown that this protein and and ORC1L are loosely associated with the core complex consisting of ORC2L, -3L, -4L and -5L. Gene silencing studies with small interfering RNA demonstrated that this protein plays an essential role in coordinating chromosome replication and segregation with cytokinesis.The origin recognition complex (ORC) is a highly conserved six subunit protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. The protein encoded by this gene is a subunit of the ORC complex. It has been shown that this protein and and ORC1L are loosely associated with the core complex consisting of ORC2L, -3L, -4L and -5L. Gene silencing studies with small interfering RNA demonstrated that this protein plays an essential role in coordinating chromosome replication and segregation with cytokinesis. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: ORC6, ORC6L
Protein Interaction Partner: LHX4, SPAG5, UBC, ORC3, CDC7, ORC4, MCM7, MCM6, MCM4, MCM2, CDC6, APP, ORC2, SUMO2, XRCC5, XRCC6, HMGA1, MCM5, TERF2, ORC5, DBF4, CDC45, RPA1,
Protein Size: 252 - Poids moléculaire
- 28 kDa
- ID gène
- 23594
- NCBI Accession
- NM_014321, NP_055136
- UniProt
- Q9Y5N6
- Pathways
- Mitotic G1-G1/S Phases, DNA Replication, M Phase, Synthesis of DNA
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