EDC4 anticorps (N-Term)

N° du produit ABIN2786009

Détail du produit anti-EDC4 anticorps

Antigène: EDC4 (Enhancer of mRNA Decapping 4 (EDC4))

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Chien, Cobaye, Cheval, Lapin, Boeuf (Vache), Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp EDC4 est non-conjugé

Application: Western Blotting (WB)

Séquence: LQEKQVICLS GDDSSTCIGI LAKEVEIVAS SDSSISSKAR GSNKVKIQPV

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 92%

Attributs du produit: This is a rabbit polyclonal antibody against EDC4. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human EDC4

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 1401 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-EDC4 (ABIN2786009)

Wang, Xu, Li, Li: "Synthesis, characterization, and antitumoral activity of polyoxometalate loaded starch nanocomplexes." dans: Journal of nanoscience and nanotechnology, Vol. 5, Issue 6, pp. 905-8, (2005) (PubMed).

Détails sur EDC4

Antigène: EDC4 (Enhancer of mRNA Decapping 4 (EDC4))

Autre désignation: EDC4 (EDC4 Produits)

Synonymes: anticorps VARICOSE, anticorps ge-1, anticorps hedls, anticorps rcd-8, anticorps GE1, anticorps Ge-1, anticorps HEDL5, anticorps HEDLS, anticorps RCD-8, anticorps RCD8, anticorps BC022641, anticorps si:ch211-237c7.1, anticorps wu:fe26b05, anticorps LRRG00115, anticorps Nrn1l, anticorps RGD1309136, anticorps enhancer of mRNA decapping 4, anticorps Transducin/WD40 repeat-like superfamily protein, anticorps enhancer of mRNA decapping 4 L homeolog, anticorps EDC4, anticorps VCS, anticorps edc4, anticorps Edc4, anticorps edc4.L

Sujet: In the process of mRNA degradation, EDC4 seems to play a role in mRNA decapping. It is the component of a complex containing DCP2 and DCP1A which functions in decapping of ARE-containing mRNAs. EDC4 promotes complex formation between DCP1A and DCP2.It enhances the catalytic activity of DCP2 (in vitro).
Alias Symbols: Ge-1, HEDLS, RCD-8
Protein Interaction Partner: MDM2, DCP1B, DCP1A, UBC, DCP2, LGR4, WWOX, RPA3, RPA2, RPA1, BMI1, DIMT1, NELFB, IGF2BP3, G3BP1, EIF2B2, EIF2B3, RFC4, NMT1, ILF2, FKBP3, DDX1, ABCF1, ZFP36, YTHDC1, EDC3, vpu, GIT2, FBLN1, CCL5, UPF1, CRK, SIRT7, EIF2AK2, Edc4, Pds5a, tat,
Protein Size: 1401

Poids moléculaire: 152 kDa

ID gène: 23644

NCBI Accession: NM_014329, NP_055144

UniProt: Q6P2E9