SESN1 anticorps (Middle Region)
-
- Antigène Voir toutes SESN1 Anticorps
- SESN1 (Sestrin 1 (SESN1))
-
Épitope
- Middle Region
-
Reactivité
- Humain, Souris, Rat, Cobaye, Cheval, Boeuf (Vache), Chien, Lapin, Poisson zèbre (Danio rerio)
-
Hôte
- Lapin
-
Clonalité
- Polyclonal
-
Conjugué
- Cet anticorp SESN1 est non-conjugé
-
Application
- Western Blotting (WB)
- Séquence
- KWLNGLENAP QKLQNLGELN KVLAHRPWLI TKEHIEGLLK AEEHSWSLAE
- Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Zebrafish: 79%
- Attributs du produit
- This is a rabbit polyclonal antibody against SESN1. It was validated on Western Blot.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the middle region of Human SESN1
- Top Product
- Discover our top product SESN1 Anticorps primaire
-
-
- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeat freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
- Antigène
- SESN1 (Sestrin 1 (SESN1))
- Autre désignation
- SESN1 (SESN1 Produits)
- Synonymes
- anticorps zgc:91970, anticorps sestrin-1, anticorps SESN1, anticorps XPA26, anticorps pa26, anticorps sest1, anticorps PA26, anticorps SEST1, anticorps 1110002G11Rik, anticorps AU044290, anticorps Pa26, anticorps Sest1, anticorps sesn1-A, anticorps sestrin 1, anticorps sestrin 1 L homeolog, anticorps SESN1, anticorps sesn1, anticorps Sesn1, anticorps sesn1.L
- Sujet
-
This gene encodes a member of the sestrin family. Sestrins are induced by the p53 tumor suppressor protein and play a role in the cellular response to DNA damage and oxidative stress. The encoded protein mediates p53 inhibition of cell growth by activating AMP-activated protein kinase, which results in the inhibition of the mammalian target of rapamycin protein. The encoded protein also plays a critical role in antioxidant defense by regenerating overoxidized peroxiredoxins, and the expression of this gene is a potential marker for exposure to radiation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Alias Symbols: PA26, SEST1
Protein Interaction Partner: UBC, RBX1, KEAP1, SQSTM1, PRDX1,
Protein Size: 551 - Poids moléculaire
- 64 kDa
- ID gène
- 27244
- NCBI Accession
- NM_014454, NP_055269
-