RABGEF1 anticorps (N-Term)

N° du produit ABIN2786039

Détail du produit anti-RABGEF1 anticorps

Antigène: RABGEF1 (RAB Guanine Nucleotide Exchange Factor (GEF) 1 (RABGEF1))

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Chévre, Cheval, Poisson zèbre (Danio rerio), Lapin, Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RABGEF1 est non-conjugé

Application: Western Blotting (WB)

Séquence: MSLKSERRGI HVDQSDLLCK KGCGYYGNPA WQGFCSKCWR EEYHKARQKQ

Homologie: Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%

Attributs du produit: This is a rabbit polyclonal antibody against RABGEF1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human RABGEF1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 491 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur RABGEF1

Antigène: RABGEF1 (RAB Guanine Nucleotide Exchange Factor (GEF) 1 (RABGEF1))

Autre désignation: RABGEF1 (RABGEF1 Produits)

Synonymes: anticorps Rab5ef, anticorps Rabex5, anticorps Rin2, anticorps RABEX5, anticorps rabex-5, anticorps rabgef1, anticorps RAB guanine nucleotide exchange factor (GEF) 1, anticorps RAB guanine nucleotide exchange factor 1, anticorps RAB guanine nucleotide exchange factor (GEF) 1 L homeolog, anticorps Rabgef1, anticorps RABGEF1, anticorps rabgef1.L

Sujet: RABGEF1 forms a complex with rabaptin-5 (RABPT5, MIM 603616) that is required for endocytic membrane fusion, and it serves as a specific guanine nucleotide exchange factor (GEF) for RAB5 (RAB5A, MIM 179512) (Horiuchi et al., 1997 [PubMed 9323142]).
Alias Symbols: FLJ32302, RABEX5, rabex-5
Protein Interaction Partner: TRIM15, CIPC, ZC2HC1C, TRIM54, RABGEF1, BLOC1S6, TXN2, THOC1, DAZAP2, UBC, TEAD4, RABEP1, DGCR6, TNKS1BP1, ROCK2, SLMAP, MON1A, RNF11, MON1B, RAB21, UBE2D3, UBE2D1, RAB5A, L1CAM, EEA1, ESR1, EGFR, RAB22A, GGA1, MAPK1, HRAS, YWHAG, YWHAB, KXD1, GGA2, RNF16
Protein Size: 491

Poids moléculaire: 57 kDa

ID gène: 27342

NCBI Accession: NM_014504, NP_055319

UniProt: A8K3R3

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process