FAM120A anticorps (Middle Region)

N° du produit ABIN2786049

Détail du produit anti-FAM120A anticorps

Antigène: FAM120A (Family with Sequence Similarity 120A (FAM120A))

Épitope: Middle Region

Reactivité: Humain, Souris, Rat, Lapin, Boeuf (Vache), Chien, Cheval, Porc

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FAM120A est non-conjugé

Application: Western Blotting (WB)

Séquence: SGGATNHISG NKIGWEKTGS HSEPQARGDP GDQTKAEGSS TASSGSQLAE

Homologie: Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 85%, Pig: 100%, Rabbit: 92%, Rat: 85%

Attributs du produit: This is a rabbit polyclonal antibody against FAM120A. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human FAM120A

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 1118 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur FAM120A

Antigène: FAM120A (Family with Sequence Similarity 120A (FAM120A))

Autre désignation: FAM120A (FAM120A Produits)

Synonymes: anticorps MGC89333, anticorps fam120a, anticorps C9orf10, anticorps Ossa, anticorps DNAPTP1, anticorps DNAPTP5, anticorps OSSA, anticorps RGD1306643, anticorps family with sequence similarity 120A, anticorps family with sequence similarity 120, member A, anticorps fam120a, anticorps Fam120a, anticorps FAM120A

Sujet: FAM120A may participate in mRNA transport in the cytoplasm. FAM120A is the critical component of the oxidative stress-induced survival signaling. It activates src family kinases and acts as a scaffolding protein enabling src family kinases to phosphorylate and activate PI3-kinase. FAM120A binds RNA and promotes the secretion of IGF-II. It may play a pivotal role in the progression of scirrhous-type gastric cancer by supporting cancer cell survival in environments with various oxidative stresses.
Alias Symbols: C9orf10, DNAPTP1, DNAPTP5, MGC111527, MGC133257, OSSA
Protein Interaction Partner: SPRTN, CEP250, SUMO2, STAU1, UBC, PASK, SUMO1, NEDD8, RNF2, EZH2, BMI1, HECW2, TARDBP, CFTR, GRK5, CAND1, CUL3, SIRT7, Ybx1,
Protein Size: 1118

Poids moléculaire: 122 kDa

ID gène: 23196

NCBI Accession: NM_014612, NP_055427

UniProt: Q9NZB2