DAAM1 anticorps (Middle Region)
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- Antigène Voir toutes DAAM1 Anticorps
- DAAM1 (Dishevelled Associated Activator of Morphogenesis 1 (DAAM1))
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Épitope
- Middle Region
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Reactivité
- Humain, Souris, Rat, Lapin, Poisson zèbre (Danio rerio), Boeuf (Vache), Cobaye, Cheval, Chien
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp DAAM1 est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- GNTVQYWLLL DRIIQQIVIQ NDKGQDPDST PLENFNIKNV VRMLVNENEV
- Homologie
- Cow: 100%, Dog: 93%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%
- Attributs du produit
- This is a rabbit polyclonal antibody against DAAM1. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the middle region of human DAAM1
- Top Product
- Discover our top product DAAM1 Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 1078 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- DAAM1 (Dishevelled Associated Activator of Morphogenesis 1 (DAAM1))
- Autre désignation
- DAAM1 (DAAM1 Produits)
- Synonymes
- anticorps 1700066F09Rik, anticorps 2310028E21Rik, anticorps AI503486, anticorps E130308H01, anticorps mKIAA0666, anticorps daam-1, anticorps xdaam1, anticorps daam1, anticorps DAAM1, anticorps DKFZp468D0524, anticorps daam1l, anticorps fc83b10, anticorps si:ch211-87i20.1, anticorps wu:fc83b10, anticorps dishevelled associated activator of morphogenesis 1, anticorps dishevelled associated activator of morphogenesis 1 S homeolog, anticorps dishevelled associated activator of morphogenesis 1a, anticorps dishevelled associated activator of morphogenesis 1b, anticorps DAAM1, anticorps Daam1, anticorps daam1.S, anticorps daam1a, anticorps daam1, anticorps daam1b
- Sujet
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Functions of the cell cortex, including motility, adhesion, and cytokinesis, are mediated by the reorganization of the actin cytoskeleton and recent evidence suggests a role for the Formin homology (FH) proteins in these processes. The protein encoded by this gene contains FH domains and belongs to a novel FH protein subfamily implicated in cell polarity. Wnt/Fz signaling activates the small GTPase Rho, a key regulator of cytoskeleton architecture, to control cell polarity and movement during development. Activation requires Dvl-Rho complex formation, an assembly mediated by this gene product, which is thought to function as a scaffolding protein.Functions of the cell cortex, including motility, adhesion, and cytokinesis, are mediated by the reorganization of the actin cytoskeleton and recent evidence suggests a role for the Formin homology (FH) proteins in these processes. The protein encoded by this gene contains FH domains and belongs to a novel FH protein subfamily implicated in cell polarity. Wnt/Fz signaling activates the small GTPase Rho, a key regulator of cytoskeleton architecture, to control cell polarity and movement during development. Activation requires Dvl-Rho complex formation, an assembly mediated by this gene product, which is thought to function as a scaffolding protein. Evidence of alternative splicing has been observed for this gene but the full-length nature of these variants has not been determined.
Alias Symbols: FLJ41657, KIAA0666
Protein Interaction Partner: UBC, PRPF40A, B3GALT4, AMBP, MAP3K7, DVL2, DVL1, RHOA,
Protein Size: 1078 - Poids moléculaire
- 123 kDa
- ID gène
- 23002
- NCBI Accession
- NM_014992, NP_055807
- UniProt
- Q9Y4D1
- Pathways
- Signalisation WNT
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