TRIB2 anticorps (Middle Region)
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- Antigène Voir toutes TRIB2 Anticorps
- TRIB2 (Tribbles Pseudokinase 2 (TRIB2))
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Épitope
- Middle Region
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Reactivité
- Humain, Souris, Rat, Chien, Lapin, Boeuf (Vache), Cheval, Poisson zèbre (Danio rerio), Cobaye
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp TRIB2 est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- YPFHDIEPSS LFSKIRRGQF NIPETLSPKA KCLIRSILRR EPSERLTSQE
- Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%
- Attributs du produit
- This is a rabbit polyclonal antibody against TRIB2. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the middle region of human TRIB2
- Top Product
- Discover our top product TRIB2 Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 343 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- TRIB2 (Tribbles Pseudokinase 2 (TRIB2))
- Autre désignation
- TRIB2 (TRIB2 Produits)
- Synonymes
- anticorps TRIB2, anticorps Trb2, anticorps Xtrbl, anticorps gs3955, anticorps c5fw, anticorps trb2, anticorps xtrb2, anticorps TRB2, anticorps C5FW, anticorps GS3955, anticorps TRB-2, anticorps AW319517, anticorps RGD1564451, anticorps tribbles pseudokinase 2, anticorps tribbles pseudokinase 2 S homeolog, anticorps TRIB2, anticorps trib2, anticorps trib2.S, anticorps Trib2
- Sujet
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TRIB2 is one of three members of the Tribbles family. The Tribbles members share a Trb domain, which is homologous to protein serine-threonine kinases, but lacks the active site lysine and probably lacks a catalytic function. The Tribbles proteins interact and modulate the activity of signal transduction pathways in a number of physiological and pathological processes. This Tribbles member induces apoptosis of cells mainly of the hematopoietic origin. It has been identified as a protein up-regulated by inflammatory stimuli in myeloid (THP-1) cells, and also as an oncogene that inactivates the transcription factor C/EBPalpha (CCAAT/enhancer-binding protein alpha) and causes acute myelogenous leukemia.
Alias Symbols: GS3955, TRB2, C5FW
Protein Interaction Partner: RFWD2, SMURF1, BTRC, PRMT6, UBC, RPS6KB1, SLAMF7, APP, UBQLN4,
Protein Size: 343 - Poids moléculaire
- 39 kDa
- ID gène
- 28951
- NCBI Accession
- NM_021643, NP_067675
- UniProt
- Q92519
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