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ALKBH3 anticorps (Middle Region)

ALKBH3 Reactivité: Humain, Souris, Rat, Cheval, Lapin, Boeuf (Vache), Chien, Cobaye, Porc WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2786204
  • Antigène Voir toutes ALKBH3 Anticorps
    ALKBH3 (AlkB, Alkylation Repair Homolog 3 (ALKBH3))
    Épitope
    • 8
    • 8
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reactivité
    Humain, Souris, Rat, Cheval, Lapin, Boeuf (Vache), Chien, Cobaye, Porc
    Hôte
    • 29
    • 2
    Lapin
    Clonalité
    • 29
    • 2
    Polyclonal
    Conjugué
    • 18
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    Cet anticorp ALKBH3 est non-conjugé
    Application
    • 20
    • 18
    • 9
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Séquence
    EMRKKPPPEE NGDYTYVERV KIPLDHGTLL IMEGATQADW QHRVPKEYHS
    Homologie
    Cow: 93%, Dog: 93%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 86%, Rat: 100%
    Attributs du produit
    This is a rabbit polyclonal antibody against ALKBH3. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogène
    The immunogen is a synthetic peptide directed towards the middle region of human ALKBH3
    Top Product
    Discover our top product ALKBH3 Anticorps primaire
  • Indications d'application
    Optimal working dilutions should be determined experimentally by the investigator.
    Commentaires

    Antigen size: 286 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Sundheim, Vågbø, Bjørås, Sousa, Talstad, Aas, Drabløs, Krokan, Tainer, Slupphaug: "Human ABH3 structure and key residues for oxidative demethylation to reverse DNA/RNA damage." dans: The EMBO journal, Vol. 25, Issue 14, pp. 3389-97, (2006) (PubMed).

  • Antigène
    ALKBH3 (AlkB, Alkylation Repair Homolog 3 (ALKBH3))
    Autre désignation
    ALKBH3 (ALKBH3 Produits)
    Sujet
    The Escherichia coli AlkB protein protects against the cytotoxicity of methylating agents by repair of the specific DNA lesions generated in single-stranded DNA. ALKBH2 (MIM 610602) and ALKBH3 are E. coli AlkB homologs that catalyze the removal of 1-methyladenine and 3-methylcytosine.The Escherichia coli AlkB protein protects against the cytotoxicity of methylating agents by repair of the specific DNA lesions generated in single-stranded DNA. ALKBH2 (MIM 610602) and ALKBH3 are E. coli AlkB homologs that catalyze the removal of 1-methyladenine and 3-methylcytosine (Duncan et al., 2002 [PubMed 12486230]).[supplied by OMIM]. Sequence Note: removed 1 base from the 5' end that did not align to the reference genome assembly. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-1519 AB042029.1 2-1520
    Alias Symbols: ABH3, DEPC-1, DEPC1, MGC118790, MGC118792, MGC118793, PCA1
    Protein Interaction Partner: AK8, LNX1, GLRX3, IKZF1, GOLGA2, SRPK2, SRPK1,
    Protein Size: 286
    Poids moléculaire
    33 kDa
    ID gène
    221120
    NCBI Accession
    NM_139178, NP_631917
    UniProt
    Q96Q83
    Pathways
    Réparation de l'ADN
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