SKA1 anticorps (Middle Region)
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- Antigène Voir toutes SKA1 Anticorps
- SKA1 (Spindle and Kinetochore Associated Complex Subunit 1 (SKA1))
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Épitope
- Middle Region
- Reactivité
- Humain, Souris, Rat, Boeuf (Vache), Chien, Cheval, Porc, Lapin
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp SKA1 est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- LLNKFELEIQ YQEQTNSSLK ELCESLREEC EDVEHLKEHV PPHLPQVTAT
- Homologie
- Cow: 93%, Dog: 93%, Horse: 86%, Human: 100%, Mouse: 93%, Pig: 79%, Rabbit: 93%, Rat: 93%
- Attributs du produit
- This is a rabbit polyclonal antibody against Ska1. It was validated on Western Blot.
- Purification
- Affinity Purified
- Top Product
- Discover our top product SKA1 Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 254 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- SKA1 (Spindle and Kinetochore Associated Complex Subunit 1 (SKA1))
- Autre désignation
- Ska1 (SKA1 Produits)
- Synonymes
- anticorps C18H18orf24, anticorps C18orf24, anticorps 2810433K01Rik, anticorps AV117428, anticorps RGD1310784, anticorps spindle and kinetochore associated complex subunit 1, anticorps SKA1, anticorps ska1, anticorps Ska1
- Sujet
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Ska1 is a Component of the SKA1 complex, a microtubule-binding subcomplex of the outer kinetochore that is essential for proper chromosome segregation. It is required for timely anaphase onset during mitosis, when chromosomes undergo bipolar attachment on spindle microtubules leading to silencing of the spindle checkpoint. The SKA1 complex is a direct component of the kinetochore-microtubule interface and directly associates with microtubules as oligomeric assemblies. The complex facilitates the processive movement of microspheres along a microtubule in a depolymerization-coupled manner. In the complex, it mediates the interaction with microtubules.
Alias Symbols: 2810433K01Rik, AV117428
Protein Size: 254 - Poids moléculaire
- 28 kDa
- ID gène
- 66468
- NCBI Accession
- NM_025581, NP_079857
- UniProt
- Q9CPV1
- Pathways
- M Phase
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