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FBXW8 anticorps (Middle Region)

FBXW8 Reactivité: Humain, Rat, Souris, Boeuf (Vache), Lapin, Cobaye, Cheval, Chien WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2786275
  • Antigène Voir toutes FBXW8 Anticorps
    FBXW8 (F-Box and WD Repeat Domain Containing 8 (FBXW8))
    Épitope
    • 15
    • 7
    • 7
    • 6
    • 6
    • 2
    • 1
    • 1
    • 1
    Middle Region
    Reactivité
    • 20
    • 15
    • 8
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Humain, Rat, Souris, Boeuf (Vache), Lapin, Cobaye, Cheval, Chien
    Hôte
    • 34
    • 1
    Lapin
    Clonalité
    • 35
    Polyclonal
    Conjugué
    • 11
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp FBXW8 est non-conjugé
    Application
    • 34
    • 17
    • 13
    • 13
    • 13
    • 12
    • 5
    • 3
    • 1
    • 1
    Western Blotting (WB)
    Séquence
    MNQKLWEVYS GHPVQHISFS SHSLITANVP YQTVMRNADL DSFTTHRRHR
    Homologie
    Cow: 83%, Dog: 92%, Guinea Pig: 83%, Horse: 92%, Human: 100%, Mouse: 92%, Rabbit: 100%, Rat: 92%
    Attributs du produit
    This is a rabbit polyclonal antibody against FBXW8. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogène
    The immunogen is a synthetic peptide directed towards the middle region of human FBXW8
    Top Product
    Discover our top product FBXW8 Anticorps primaire
  • Indications d'application
    Optimal working dilutions should be determined experimentally by the investigator.
    Commentaires

    Antigen size: 598 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Lin, Fu, Zhao, Lin, Zou, Liu, Zhu, Wang, Yu: "Fbxw8 is involved in the proliferation of human choriocarcinoma JEG-3 cells." dans: Molecular biology reports, Vol. 38, Issue 3, pp. 1741-7, (2011) (PubMed).

  • Antigène
    FBXW8 (F-Box and WD Repeat Domain Containing 8 (FBXW8))
    Autre désignation
    FBXW8 (FBXW8 Produits)
    Synonymes
    anticorps FBW6, anticorps FBW8, anticorps FBX29, anticorps FBXO29, anticorps FBXW6, anticorps 4930438M06Rik, anticorps Fbx29, anticorps F-box and WD repeat domain containing 8, anticorps ring finger protein, transmembrane 2, anticorps F-box and WD-40 domain protein 8, anticorps FBXW8, anticorps Fbxw8, anticorps RNFT2
    Sujet
    FBXW8 is a member of the F-box protein family, members of which are characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into three classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. FBXW8 contains a WD-40 domain, in addition to an F-box motif, so it belongs to the Fbw class.This gene encodes a member of the F-box protein family, members of which are characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into three classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene contains a WD-40 domain, in addition to an F-box motif, so it belongs to the Fbw class. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene.
    Alias Symbols: FBW6, FBW8, FBX29, FBXO29, MGC33534, FBXW6
    Protein Interaction Partner: MAP4K1, CUL1, TBC1D3, CUL7, UBE2D3, SKP1, IRS1, REST, CCND1, CUL4A, DDB1, UBC, CCDC8, GORASP1, OBSL1, CCT6B, CCT2, CCT7, TRIP13, PDCD5, CUL2, VBP1, CCT3, PFDN5, NFKBIA, CCT6A, BCL3, BTRC, SKP2, HSP90AA1, HSPA4, FBXO4, FBXW8, FBXW2, MYC, RBX1, UBI4, EP300,
    Protein Size: 598
    Poids moléculaire
    67 kDa
    ID gène
    26259
    NCBI Accession
    NM_153348, NP_699179
    UniProt
    Q8N3Y1
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