COX18 anticorps (Middle Region)

N° du produit ABIN2786331

Détail du produit anti-COX18 anticorps

Antigène: COX18 (Cytochrome C Oxidase Assembly Homolog 18 (COX18))

Épitope: Middle Region

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Cheval, Lapin, Porc

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp COX18 est non-conjugé

Application: Western Blotting (WB)

Séquence: LCSSFVGLSQ NLLLRSPGFR QLCRIPSTKS DSETPYKDIF AAFNTKFISR

Homologie: Cow: 79%, Dog: 79%, Horse: 86%, Human: 100%, Mouse: 85%, Pig: 86%, Rabbit: 86%, Rat: 93%

Attributs du produit: This is a rabbit polyclonal antibody against COX18. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human COX18

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 333 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur COX18

Antigène: COX18 (Cytochrome C Oxidase Assembly Homolog 18 (COX18))

Autre désignation: COX18 (COX18 Produits)

Synonymes: anticorps COX18HS, anticorps BC038311, anticorps RGD1559547, anticorps COX18 cytochrome c oxidase assembly factor L homeolog, anticorps COX18, cytochrome c oxidase assembly factor, anticorps cytochrome c oxidase assembly protein 18, anticorps cox18.L, anticorps COX18, anticorps Cox18

Sujet: COX18 is required for the insertion of integral membrane proteins into the mitochondrial inner membrane. COX18 is essential for the activity and assembly of cytochrome c oxidase. COX18 plays a central role in the translocation and export of the C-terminal part of the COX2 protein into the mitochondrial intermembrane space.COX18 encodes a cytochrome c oxidase (COX)-assembly protein. The S. cerevisiae Cox18 protein catalyzes the insertion of the Cox2 (MTCO2, MIM 516040) C-terminal tail into the mitochondrial inner membrane, an intermediate step in the assembly of complex IV of the mitochondrial respiratory chain (Sacconi et al., 2005 [PubMed 16212937]).[supplied by OMIM]. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-1248 AY957565.1 1-1248 1249-4523 AC095053.3 75071-78345 c
Alias Symbols: COX18HS, FLJ38991, MGC126733
Protein Size: 333

Poids moléculaire: 37 kDa

ID gène: 285521

NCBI Accession: NM_173827, NP_776188

UniProt: Q8N8Q8