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RHOC anticorps (N-Term)

RHOC Reactivité: Humain, Souris, Rat, Chien, Lapin, Boeuf (Vache), Cobaye, Poisson zèbre (Danio rerio), Cheval, Saccharomyces cerevisiae, Chévre, Mouton WB, IHC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2786344
  • Antigène Voir toutes RHOC Anticorps
    RHOC (Ras Homolog Gene Family, Member C (RHOC))
    Épitope
    • 9
    • 8
    • 5
    • 5
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivité
    • 42
    • 18
    • 8
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain, Souris, Rat, Chien, Lapin, Boeuf (Vache), Cobaye, Poisson zèbre (Danio rerio), Cheval, Saccharomyces cerevisiae, Chévre, Mouton
    Hôte
    • 35
    • 8
    Lapin
    Clonalité
    • 36
    • 6
    Polyclonal
    Conjugué
    • 22
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp RHOC est non-conjugé
    Application
    • 31
    • 26
    • 15
    • 5
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Séquence
    VPTVFENYIA DIEVDGKQVE LALWDTAGQE DYDRLRPLSY PDTDVILMCF
    Homologie
    Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Yeast: 100%, Zebrafish: 100%
    Attributs du produit
    This is a rabbit polyclonal antibody against RHOC. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogène
    The immunogen is a synthetic peptide directed towards the N terminal region of human RHOC
    Top Product
    Discover our top product RHOC Anticorps primaire
  • Indications d'application
    Optimal working dilutions should be determined experimentally by the investigator.
    Commentaires

    Antigen size: 193 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Sousa, Espreafico: "Suppression subtractive hybridization profiles of radial growth phase and metastatic melanoma cell lines reveal novel potential targets." dans: BMC cancer, Vol. 8, pp. 19, (2008) (PubMed).

  • Antigène
    RHOC (Ras Homolog Gene Family, Member C (RHOC))
    Autre désignation
    RHOC (RHOC Produits)
    Synonymes
    anticorps ARHC, anticorps LOC100221682, anticorps ARH9, anticorps H9, anticorps RHOH9, anticorps AI324259, anticorps Arh9, anticorps Arhc, anticorps CRHOC, anticorps ras homolog family member C L homeolog, anticorps ras homolog family member C, anticorps rhoc.L, anticorps RHOC, anticorps rhoc, anticorps Rhoc
    Sujet
    RHOC Is a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades. Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility. RHOC is prenylated at its C-terminus, and localizes to the cytoplasm and plasma membrane. It is thought to be important in cell locomotion. Overexpression of RHOC is associated with tumor cell proliferation and metastasis.This gene encodes a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades. Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility. The protein encoded by this gene is prenylated at its C-terminus, and localizes to the cytoplasm and plasma membrane. It is thought to be important in cell locomotion. Overexpression of this gene is associated with tumor cell proliferation and metastasis. Multiple alternatively spliced variants, encoding the same protein, have been identified.
    Alias Symbols: ARH9, ARHC, H9, MGC1448, MGC61427, RHOH9
    Protein Interaction Partner: FAM65B, UBC, env, ATF2, PPP3CA, CDK2, LNX1, CAV1, CIT, ARHGAP1, RTKN, DIAPH1, ROCK1, VHL, ARHGDIA,
    Protein Size: 193
    Poids moléculaire
    22 kDa
    ID gène
    389
    NCBI Accession
    NM_175744, NP_786886
    UniProt
    P08134
    Pathways
    Signalisation WNT, Cell-Cell Junction Organization
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