RHOC anticorps (N-Term)
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- Antigène Voir toutes RHOC Anticorps
- RHOC (Ras Homolog Gene Family, Member C (RHOC))
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Épitope
- N-Term
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Reactivité
- Humain, Souris, Rat, Chien, Lapin, Boeuf (Vache), Cobaye, Poisson zèbre (Danio rerio), Cheval, Saccharomyces cerevisiae, Chévre, Mouton
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp RHOC est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Séquence
- VPTVFENYIA DIEVDGKQVE LALWDTAGQE DYDRLRPLSY PDTDVILMCF
- Homologie
- Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Yeast: 100%, Zebrafish: 100%
- Attributs du produit
- This is a rabbit polyclonal antibody against RHOC. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the N terminal region of human RHOC
- Top Product
- Discover our top product RHOC Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 193 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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Suppression subtractive hybridization profiles of radial growth phase and metastatic melanoma cell lines reveal novel potential targets." dans: BMC cancer, Vol. 8, pp. 19, (2008) (PubMed).
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Suppression subtractive hybridization profiles of radial growth phase and metastatic melanoma cell lines reveal novel potential targets." dans: BMC cancer, Vol. 8, pp. 19, (2008) (PubMed).
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- Antigène
- RHOC (Ras Homolog Gene Family, Member C (RHOC))
- Autre désignation
- RHOC (RHOC Produits)
- Synonymes
- anticorps ARHC, anticorps LOC100221682, anticorps ARH9, anticorps H9, anticorps RHOH9, anticorps AI324259, anticorps Arh9, anticorps Arhc, anticorps CRHOC, anticorps ras homolog family member C L homeolog, anticorps ras homolog family member C, anticorps rhoc.L, anticorps RHOC, anticorps rhoc, anticorps Rhoc
- Sujet
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RHOC Is a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades. Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility. RHOC is prenylated at its C-terminus, and localizes to the cytoplasm and plasma membrane. It is thought to be important in cell locomotion. Overexpression of RHOC is associated with tumor cell proliferation and metastasis.This gene encodes a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades. Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility. The protein encoded by this gene is prenylated at its C-terminus, and localizes to the cytoplasm and plasma membrane. It is thought to be important in cell locomotion. Overexpression of this gene is associated with tumor cell proliferation and metastasis. Multiple alternatively spliced variants, encoding the same protein, have been identified.
Alias Symbols: ARH9, ARHC, H9, MGC1448, MGC61427, RHOH9
Protein Interaction Partner: FAM65B, UBC, env, ATF2, PPP3CA, CDK2, LNX1, CAV1, CIT, ARHGAP1, RTKN, DIAPH1, ROCK1, VHL, ARHGDIA,
Protein Size: 193 - Poids moléculaire
- 22 kDa
- ID gène
- 389
- NCBI Accession
- NM_175744, NP_786886
- UniProt
- P08134
- Pathways
- Signalisation WNT, Cell-Cell Junction Organization
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