NUP43 anticorps (Middle Region)

N° du produit ABIN2786439

Détail du produit anti-NUP43 anticorps

Antigène: NUP43 (Nucleoporin 43kDa (NUP43))

Épitope: Middle Region

Reactivité: Humain, Souris, Rat, Lapin, Boeuf (Vache), Chien, Cobaye, Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NUP43 est non-conjugé

Application: Western Blotting (WB)

Séquence: HQSVISSWLS TDPAKDRIEI TSLLPSRSLS VNTLDVLGPC LVCGTDAEAI

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against NUP43. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human NUP43

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 380 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-NUP43 (ABIN2786439)

Mehrle, Rosenfelder, Schupp, del Val, Arlt, Hahne, Bechtel, Simpson, Hofmann, Hide, Glatting, Huber, Pepperkok, Poustka, Wiemann: "The LIFEdb database in 2006." dans: Nucleic acids research, Vol. 34, Issue Database issue, pp. D415-8, (2005) (PubMed).

Détails sur NUP43

Antigène: NUP43 (Nucleoporin 43kDa (NUP43))

Autre désignation: NUP43 (NUP43 Produits)

Synonymes: anticorps MGC184722, anticorps MGC154553, anticorps 2610016K01Rik, anticorps 2610529I12Rik, anticorps AA409950, anticorps p42, anticorps bA350J20.1, anticorps nucleoporin 43, anticorps nucleoporin 43kDa, anticorps nucleoporin Nup43, anticorps nucleoporin 43kDa S homeolog, anticorps NUP43, anticorps nup43, anticorps LOC696374, anticorps nup43.S, anticorps Nup43

Sujet: NUP43 is the component of the Nup107-160 subcomplex of the nuclear pore complex (NPC). The Nup107-160 subcomplex is required for the assembly of a functional NPC. The Nup107-160 subcomplex is also required for normal kinetochore microtubule attachment, mitotic progression and chromosome segregation.Bidirectional transport of macromolecules between the cytoplasm and nucleus occurs through nuclear pore complexes (NPCs) embedded in the nuclear envelope. NPCs are composed of subcomplexes, and NUP43 is part of one such subcomplex, Nup107-160 (Loiodice et al., 2004 [PubMed 15146057]).[supplied by OMIM]. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-10 BG567254.1 2-11 11-24 CB989591.1 28-41 25-47 AK074311.1 1-23 48-1751 AF514997.1 1-1704 1752-2581 BC047539.1 2681-3510 2582-2745 BC046637.1 2350-2513 2746-2818 BG527619.1 33-105 c 2819-3862 BC046637.1 2587-3630
Alias Symbols: FLJ13287, bA350J20.1, p42
Protein Interaction Partner: UBC, SUMO1, SEH1L, DCTN2, TP53RK, RAB3GAP2, NUP107, UBD, ISG15, CUL4A, DDB1, Nup98, NUP37, NUP85, NUP133, NUP160,
Protein Size: 380

Poids moléculaire: 42 kDa

ID gène: 348995

NCBI Accession: NM_198887, NP_942590

UniProt: Q8NFH3