PPOX anticorps (N-Term)

N° du produit ABIN2786509

Détail du produit anti-PPOX anticorps

Antigène: PPOX (Protoporphyrinogen Oxidase (PPOX))

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Lapin, Boeuf (Vache), Cobaye, Cheval, Chien, Porc

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PPOX est non-conjugé

Application: Western Blotting (WB)

Séquence: SSERLGGWIR SVRGPNGAIF ELGPRGIRPA GALGARTLLL VSELGLDSEV

Homologie: Cow: 100%, Dog: 93%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against PPOX. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human PPOX

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 477 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-PPOX (ABIN2786509)

de Vooght, van Wijk, van Solinge: "GATA-1 binding sites in exon 1 direct erythroid-specific transcription of PPOX." dans: Gene, Vol. 409, Issue 1-2, pp. 83-91, (2008) (PubMed).

Détails sur PPOX

Antigène: PPOX (Protoporphyrinogen Oxidase (PPOX))

Autre désignation: PPOX (PPOX Produits)

Synonymes: anticorps PPO, anticorps V290M, anticorps VP, anticorps Ppo, anticorps BcDNA:LD41392, anticorps CG5796, anticorps Dmel\\CG5796, anticorps ESTS:9F2T, anticorps zgc:123252, anticorps HEMG1, anticorps PPO1, anticorps PROTOPORPHYRINOGEN OXIDASE, anticorps TC0121, anticorps hemG, anticorps protoporphyrinogen oxidase, anticorps Protoporphyrinogen oxidase, anticorps Flavin containing amine oxidoreductase family, anticorps polyphenol oxidase, chloroplastic, anticorps PPOX, anticorps Ppox, anticorps ppox, anticorps hemY, anticorps TC_RS00645, anticorps Mrub_1406, anticorps Mesil_2992, anticorps Trad_0583, anticorps Calni_0746, anticorps Ocepr_1049, anticorps Tmar_0766, anticorps Intca_1907, anticorps Despr_0642, anticorps Plabr_2407, anticorps Deipr_2130, anticorps Hipma_0622, anticorps LOC110782963

Sujet: PPOX catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX..This gene encodes the penultimate enzyme of heme biosynthesis, which catalyzes the 6-electron oxidation of protoporphyrinogen IX to form protoporphyrin IX. Mutations in this gene cause variegate porphyria, an autosomal dominant disorder of heme metabolism resulting from a deficiency in protoporphyrinogen oxidase, an enzyme located on the inner mitochondrial membrane. Alternatively spliced transcript variants encoding the same protein have been identified.
Alias Symbols: MGC8485, PPO, V290M, VP
Protein Interaction Partner: HNRNPD, UBC, COPS5, HAP1, PPOX, IMMT,
Protein Size: 477

Poids moléculaire: 51 kDa

ID gène: 5498

NCBI Accession: NM_000309, NP_000300

UniProt: P50336

Pathways: Synaptic Membrane, Feeding Behaviour