PEX5 anticorps (N-Term)
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- Antigène Voir toutes PEX5 Anticorps
- PEX5 (Peroxisomal Biogenesis Factor 5 (PEX5))
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Épitope
- N-Term
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Reactivité
- Humain, Souris, Rat, Chien, Cheval, Lapin, Cobaye, Boeuf (Vache)
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp PEX5 est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- TATDRWYDEY HPEEDLQHTA SDFVAKVDDP KLANSEFLKF VRQIGEGQVS
- Homologie
- Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
- Attributs du produit
- This is a rabbit polyclonal antibody against PEX5. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the N terminal region of human PEX5
- Top Product
- Discover our top product PEX5 Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 631 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- PEX5 (Peroxisomal Biogenesis Factor 5 (PEX5))
- Autre désignation
- PEX5 (PEX5 Produits)
- Synonymes
- anticorps AW212715, anticorps ESTM1, anticorps PTS1R, anticorps Pxr1, anticorps X83306, anticorps PTS1-BP, anticorps PBD2A, anticorps PBD2B, anticorps PXR1, anticorps Peroxin-5, anticorps peroxisomal biogenesis factor 5, anticorps pex5, anticorps Pex5, anticorps PEX5
- Sujet
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PEX5 binds to the C-terminal PTS1-type tripeptide peroxisomal targeting signal (SKL-type) and plays an essential role in peroxisomal protein import. Peroxins (PEXs) are proteins that are essential for the assembly of functional peroxisomes. The peroxisome biogenesis disorders (PBDs) are a group of genetically heterogeneous autosomal recessive, lethal diseases characterized by multiple defects in peroxisome function. The peroxisomal biogenesis disorders are a heterogeneous group with at least 14 complementation groups and with more than 1 phenotype being observed in cases falling into particular complementation groups. Although the clinical features of PBD patients vary, cells from all PBD patients exhibit a defect in the import of one or more classes of peroxisomal matrix proteins into the organelle. Defects in this gene are a cause of neonatal adrenoleukodystrophy (NALD), a cause of Zellweger syndrome (ZWS) as well as may be a cause of infantile Refsum disease (IRD).
Alias Symbols: PTS1R, PXR1, PTS1-BP
Protein Interaction Partner: CAPRIN2, CCDC14, TOMM7, PRR13, GDPD5, ZNF772, EP400NL, TM6SF1, ACOT8, RPL14, MKRN3, S100A6, LDHB, RANBP6, GSTK1, ZADH2, TYSND1, HSDL2, ACAD11, LONP2, PECR, HSD17B4, HOXA7, EHHADH, ECH1, CRAT, CAT, BRCA1, ACOX1, DECR2, HACL1, DHRS4, ECI2, AGPS, GNPAT, UBC,
Protein Size: 631 - Poids moléculaire
- 70 kDa
- ID gène
- 5830
- NCBI Accession
- NM_000319, NP_000310
- Pathways
- Monocarboxylic Acid Catabolic Process
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