BLMH anticorps (Middle Region)
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- Antigène Voir toutes BLMH Anticorps
- BLMH (Bleomycin Hydrolase (BLMH))
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Épitope
- Middle Region
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Reactivité
- Humain, Rat, Souris, Poisson zèbre (Danio rerio), Chien, Cobaye, Boeuf (Vache), Cheval, Lapin
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp BLMH est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- EYLSNMVGGR KTLYNNQPID FLKKMVAASI KDGEAVWFGC DVGKHFNSKL
- Homologie
- Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 85%
- Attributs du produit
- This is a rabbit polyclonal antibody against BLMH. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the middle region of human BLMH
- Top Product
- Discover our top product BLMH Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 455 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- BLMH (Bleomycin Hydrolase (BLMH))
- Autre désignation
- BLMH (BLMH Produits)
- Synonymes
- anticorps AI035728, anticorps Bh, anticorps Bmh, anticorps wu:fb13c01, anticorps zgc:66261, anticorps bh, anticorps bmh, anticorps BH, anticorps BMH, anticorps bleomycin hydrolase, anticorps Bleomycin hydrolase, anticorps bleomycin hydrolase S homeolog, anticorps BLMH, anticorps pepC, anticorps LOC5569945, anticorps Apre_0140, anticorps Apar_0899, anticorps Smon_1289, anticorps Kfla_1242, anticorps Snas_3912, anticorps BLJ_1941, anticorps Olsu_1085, anticorps PGTDC60_0106, anticorps Blmh, anticorps blmh, anticorps blmh.S
- Sujet
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The normal physiological role of BLM hydrolase is unknown, but it catalyzes the inactivation of the antitumor drug BLM (a glycopeptide) by hydrolyzing the carboxamide bond of its B-aminoalaninamide moiety thus protecting normal and malignant cells from BLM toxicity.Bleomycin hydrolase (BMH) is a cytoplasmic cysteine peptidase that is highly conserved through evolution, however, the only known activity of the enzyme is metabolic inactivation of the glycopeptide bleomycin (BLM), an essential component of combination chemotherapy regimens for cancer. The protein contains the signature active site residues of the cysteine protease papain superfamily. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: BH, BMH
Protein Interaction Partner: NUDT12, WDYHV1, BLMH, UBC, ZBTB1, SH3GLB2, LZTFL1, GORASP2, PES1, GTF2A1, AP1M2, CYP2C8, RNF32, ECSIT, MAST1, COPS5, CUL4B, SUMO2, PDPK1, Fam134a, USP53, KBTBD7, RPL11, UBE2I, TRIO, RPL29, APP,
Protein Size: 455 - Poids moléculaire
- 52 kDa
- ID gène
- 642
- NCBI Accession
- NM_000386, NP_000377
- UniProt
- Q13867
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