Sec8 anticorps (N-Term)

N° du produit ABIN2786600

Détail du produit anti-Sec8 anticorps

Antigène: Sec8 (EXOC4) (Exocyst Complex Component 4 (EXOC4))

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Cheval, Porc, Lapin, Chien, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Sec8 est non-conjugé

Application: Western Blotting (WB)

Séquence: MAAEAAGGKY RSTVSKSKDP SGLLISVIRT LSTSDDVEDR ENEKGRLEEA

Homologie: Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 85%

Attributs du produit: This is a rabbit polyclonal antibody against EXOC4. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human EXOC4

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 473 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur Sec8

Antigène: Sec8 (EXOC4) (Exocyst Complex Component 4 (EXOC4))

Autre désignation: EXOC4 (EXOC4 Produits)

Synonymes: anticorps CG2095, anticorps Dmel\\CG2095, anticorps Sec8, anticorps Sec8p, anticorps dsec8, anticorps fun, anticorps SEC8L1, anticorps DKFZp459N1430, anticorps SEC8, anticorps C78892, anticorps Sec8l1, anticorps ALR, anticorps si:ch211-92l17.2, anticorps si:rp71-18a24.2, anticorps ATSEC8, anticorps SUBUNIT OF EXOCYST COMPLEX 8, anticorps subunit of exocyst complex 8, anticorps Secretory 8, anticorps exocyst complex component 4, anticorps exocyst complex component 4 L homeolog, anticorps Exocyst complex component 4, anticorps subunit of exocyst complex 8, anticorps Sec8, anticorps EXOC4, anticorps CpipJ_CPIJ001354, anticorps Exoc4, anticorps exoc4, anticorps exoc4.L, anticorps sec-8, anticorps SEC8

Sujet: The specific function of this protein remains unknown.The protein encoded by this gene is a component of the exocyst complex, a multiple protein complex essential for targeting exocytic vesicles to specific docking sites on the plasma membrane. Though best characterized in yeast, the component proteins and functions of exocyst complex have been demonstrated to be highly conserved in higher eukaryotes. At least eight components of the exocyst complex, including this protein, are found to interact with the actin cytoskeletal remodeling and vesicle transport machinery. The complex is also essential for the biogenesis of epithelial cell surface polarity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Alias Symbols: MGC27170, REC8, SEC8, SEC8L1, Sec8p
Protein Interaction Partner: SUMO2, UBC, EXOC2, EXOC7, ATG5, ATG12, BECN1, EXOC8, EGFR, EXOC1, EXOC3, nef, IQCB1, EXOC5, UBD, MYO5A, DTNBP1, CEP63, DISC1, Poc1b, GTF2E2, DLGAP4, DLG3, RALA, GRIN2B, DLG4, MYC,
Protein Size: 473

Poids moléculaire: 54 kDa

ID gène: 60412

NCBI Accession: NM_001037126, NP_001032203

UniProt: Q8TAR2

Pathways: Peptide Hormone Metabolism, Synaptic Vesicle Exocytosis