PSME2 anticorps (Middle Region)
-
- Antigène Voir toutes PSME2 Anticorps
- PSME2 (Proteasome (Prosome, Macropain) Activator Subunit 2 (PA28 Beta) (PSME2))
-
Épitope
- Middle Region
-
Reactivité
- Humain, Souris, Rat, Chien, Cheval, Poisson zèbre (Danio rerio), Boeuf (Vache), Cobaye, Porc, Lapin
-
Hôte
- Lapin
-
Clonalité
- Polyclonal
-
Conjugué
- Cet anticorp PSME2 est non-conjugé
-
Application
- Western Blotting (WB)
- Séquence
- QEKVLERVNA VKTKVEAFQT TISKYFSERG DAVAKASKET HVMDYRALVH
- Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 93%, Rat: 100%, Zebrafish: 79%
- Attributs du produit
- This is a rabbit polyclonal antibody against PSME2. It was validated on Western Blot.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the middle region of human PSME2
- Top Product
- Discover our top product PSME2 Anticorps primaire
-
-
- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
-
Antigen size: 239 AA
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
- Antigène
- PSME2 (Proteasome (Prosome, Macropain) Activator Subunit 2 (PA28 Beta) (PSME2))
- Autre désignation
- PSME2 (PSME2 Produits)
- Synonymes
- anticorps unp309, anticorps PA28B, anticorps PA28beta, anticorps REGbeta, anticorps AA589371, anticorps AI788882, anticorps PA28b, anticorps proteasome activator subunit 2, anticorps proteasome (prosome, macropain) activator subunit 2 (PA28 beta), anticorps psme2, anticorps PSME2, anticorps Psme2
- Sujet
-
The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. The immunoproteasome contains an alternate regulator, referred to as the 11S regulator or PA28, that replaces the 19S regulator. Three subunits (alpha, beta and gamma) of the 11S regulator have been identified. This gene encodes the beta subunit of the 11S regulator, one of the two 11S subunits that is induced by gamma-interferon. Three beta and three alpha subunits combine to form a heterohexameric ring. Six pseudogenes have been identified on chromosomes 4, 5, 8, 10 and 13.
Alias Symbols: PA28B, PA28beta, REGbeta
Protein Interaction Partner: NAA10, PSMD14, SHFM1, UBC, PSME2, PSME1, PARK2, BAG3, NHLH1, MYOD1, EPHA2, CFTR, DDTL, TNN, CAP1, PTMA, PSMD7, PSMD2, PSMD1, PSMC5, PSMC4, PSMC2, PSMB5, PSMB3, PSMB1, PSMA6, PSMA5, PSMA3, PSMA2, PSMA1, GARS, APP, PSMC1, PSMD6, PSMB10, PSMB9, PSMB8, PSMB7,
Protein Size: 239 - Poids moléculaire
- 27 kDa
- ID gène
- 5721
- NCBI Accession
- NM_002818, NP_002809
- UniProt
- Q9UL46
- Pathways
- Mitotic G1-G1/S Phases, DNA Replication, Positive Regulation of Endopeptidase Activity, Synthesis of DNA
-