RANGAP1 anticorps (N-Term)

N° du produit ABIN2786743

Détail du produit anti-RANGAP1 anticorps

Antigène: RANGAP1 (Ran GTPase Activating Protein 1 (RANGAP1))

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Chien, Boeuf (Vache), Cheval, Lapin, Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RANGAP1 est non-conjugé

Application: Western Blotting (WB)

Séquence: MASEDIAKLA ETLAKTQVAG GQLSFKGKSL KLNTAEDAKD VIKEIEDFDS

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against RANGAP1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human RANGAP1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 587 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-RANGAP1 (ABIN2786743)

Ewing, Chu, Elisma, Li, Taylor, Climie, McBroom-Cerajewski, Robinson, OConnor, Li, Taylor, Dharsee, Ho, Heilbut, Moore, Zhang, Ornatsky, Bukhman, Ethier, Sheng, Vasilescu, Abu-Farha, Lambert, Duewel et al.: "Large-scale mapping of human protein-protein interactions by mass spectrometry. ..." dans: Molecular systems biology, Vol. 3, pp. 89, (2007) (PubMed).

Détails sur RANGAP1

Antigène: RANGAP1 (Ran GTPase Activating Protein 1 (RANGAP1))

Autre désignation: RANGAP1 (RANGAP1 Produits)

Synonymes: anticorps Fug1, anticorps RANGAP, anticorps SD, anticorps ATRANGAP1, anticorps RAN GTPASE-ACTIVATING PROTEIN 1, anticorps RAN GTPase activating protein 1, anticorps RanGAP1, anticorps fug1, anticorps rangap1b, anticorps rna1p, anticorps C79654, anticorps mKIAA1835, anticorps rangap1, anticorps rangap1a, anticorps Protein rna1, anticorps CG9999, anticorps CT28175, anticorps Dmel\CG9999, anticorps RGP1_DROME, anticorps Ran, anticorps RanGAP, anticorps RanGap, anticorps RanGap1, anticorps Scl, anticorps Sd, anticorps Sd-RanGAP, anticorps Sd-RanGap, anticorps dRanGAP, anticorps ranGAP, anticorps ranGap, anticorps rangap, anticorps zgc:154097, anticorps Ran GTPase activating protein 1, anticorps RAN GTPase activating protein 1, anticorps ran GTPase activating protein 1, anticorps Ran GTPase activating protein 1 S homeolog, anticorps Ran GTPase activating protein 1 L homeolog, anticorps Ran GAP Rna1, anticorps Ran GTPase activating protein, anticorps RAN GTPase activating protein 1a, anticorps RANGAP1, anticorps TERG_02084, anticorps rangap1.S, anticorps Rangap1, anticorps rangap1.L, anticorps rna1, anticorps RanGAP, anticorps rangap1a

Sujet: RanGAP1, is a homodimeric 65-kD polypeptide that specifically induces the GTPase activity of RAN, but not of RAS by over 1,000-fold. RanGAP1 is the immediate antagonist of RCC1, a regulator molecule that keeps RAN in the active, GTP-bound state. The RANGA
Alias Symbols: Fug1, KIAA1835, MGC20266, SD
Protein Interaction Partner: SENP2, SENP1, SUMO1, UBE2I, SUMO2, SUMO3, RANBP2, UBC, NEDD8, RNF2, rev, TP53RK, EFTUD1, NIF3L1, RPRD1B, OSGEP, PANK4, THG1L, NSUN2, UFM1, IPO11, SH3GLB1, TPRKB, EEF2K, DBNL, KIAA1279, ACTR2, ACTR3, ARPC1B, SAE1, TPD52L2, PPP2R5D, LPP, CALU, BAG1, ARPC2,
Protein Size: 587

Poids moléculaire: 63 kDa

ID gène: 5905

NCBI Accession: NM_002883, NP_002874

UniProt: P46060

Pathways: M Phase, Protein targeting to Nucleus