PINX1 anticorps (Middle Region)

N° du produit ABIN2787041

Détail du produit anti-PINX1 anticorps

Antigène: PINX1 (PIN2/TERF1 Interacting, Telomerase Inhibitor 1 (PINX1))

Épitope: Middle Region

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Cheval, Lapin, Porc, Cobaye, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PINX1 est non-conjugé

Application: Western Blotting (WB)

Séquence: EKKSFSLEEK SKISKNRVHY MKFTKGKDLS SRSKTDLDCI FGKRQSKKTP

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 92%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%

Attributs du produit: This is a rabbit polyclonal antibody against PINX1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human PINX1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 328 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur PINX1

Antigène: PINX1 (PIN2/TERF1 Interacting, Telomerase Inhibitor 1 (PINX1))

Autre désignation: PINX1 (PINX1 Produits)

Synonymes: anticorps PINX1, anticorps LPTL, anticorps LPTS, anticorps 2210403I16Rik, anticorps 2610028A01Rik, anticorps 67-11-3, anticorps AU024023, anticorps LPTS1, anticorps RGD1566025, anticorps PIN2/TERF1 interacting telomerase inhibitor 1, anticorps PIN2/TERF1 interacting, telomerase inhibitor 1, anticorps PINX1, anticorps Pinx1

Sujet: PINX1 is a microtubule-binding protein essential for faithful chromosome segregation. PINX1 mediates TRF1 and TERT accumulation in nucleolus and enhances TRF1 binding to telomeres. PINX1 inhibits telomerase activity and may inhibit cell proliferation and act as tumor suppressor.
Alias Symbols: FLJ20565, LPTL, LPTS, MGC8850
Protein Interaction Partner: UBC, CACYBP, TP63, GABPA, TERF1, DHX15, AIDA, MCRS1, PAFAH1B2, TERT, MPZ, HRNR, PLEKHJ1, PABPC1, GTPBP4, PABPC4, TXN, RPS28, RPS19, RPS16, RPS10, RPS3A, RPL31, RPL23A, CAPRIN1, CALM3, AHCY,
Protein Size: 328

Poids moléculaire: 37 kDa

ID gène: 54984

NCBI Accession: NM_017884, NP_060354

UniProt: Q96BK5