TDP1 anticorps (Middle Region)
-
- Antigène Voir toutes TDP1 Anticorps
- TDP1 (Tyrosyl-DNA Phosphodiesterase 1 (TDP1))
-
Épitope
- Middle Region
-
Reactivité
- Humain, Souris, Rat, Cheval, Boeuf (Vache), Cobaye, Chien, Lapin
-
Hôte
- Lapin
-
Clonalité
- Polyclonal
-
Conjugué
- Cet anticorp TDP1 est non-conjugé
-
Application
- Western Blotting (WB)
- Séquence
- ETNVYLIGST PGRFQGSHRD NWGHFRLRKL LQAHAPSTPK GECWPIVGQF
- Homologie
- Cow: 92%, Dog: 93%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 86%, Rabbit: 93%, Rat: 100%
- Attributs du produit
- This is a rabbit polyclonal antibody against Tdp1. It was validated on Western Blot.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide corresponding to a region of Mouse
- Top Product
- Discover our top product TDP1 Anticorps primaire
-
-
- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
-
Antigen size: 579 AA
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
- Antigène
- TDP1 (Tyrosyl-DNA Phosphodiesterase 1 (TDP1))
- Autre désignation
- Tdp1 (TDP1 Produits)
- Synonymes
- anticorps 2810481F14Rik, anticorps 4921509N21Rik, anticorps AI838772, anticorps AW493413, anticorps E430034L06Rik, anticorps MLZ-501, anticorps SCAN1, anticorps tdp1, anticorps MGC83708, anticorps TDP1, anticorps F8M21.60, anticorps F8M21_60, anticorps tyrosyl-DNA phosphodiesterase 1, anticorps tyrosyl-DNA phosphodiesterase 1, anticorps tyrosyl-DNA Phosphodiesterase (Tdp1), anticorps tyrosyl-DNA phosphodiesterase 1 L homeolog, anticorps tyrosyl-DNA phosphodiesterase-like protein, anticorps TDP1, anticorps Tc00.1047053511191.10, anticorps Tdp1, anticorps tdp1.L, anticorps tdp1, anticorps PTRG_11198, anticorps MCYG_02121, anticorps MGYG_03035
- Sujet
-
Tdp1 is a DNA repair enzyme that can remove a variety of covalent adducts from DNA through hydrolysis of a 3'-phosphodiester bond, giving rise to DNA with a free 3' phosphate. It catalyzes the hydrolysis of dead-end complexes between DNA and the topoisomerase I active site tyrosine residue. It hydrolyzes 3'-phosphoglycolates on protruding 3' ends on DNA double-strand breaks due to DNA damage by radiation and free radicals. It acts on blunt-ended double-strand DNA breaks and on single-stranded DNA. It has low 3'exonuclease activity and can remove a single nucleoside from the 3'end of DNA and RNA molecules with 3'hydroxyl groups. It has no exonuclease activity towards DNA or RNA with a 3'phosphate.
Alias Symbols: 2810481F14Rik, 4921509N21Rik, AI838772, AW493413, E430034L06Rik, SCAN1, MLZ-501
Protein Size: 579 - Poids moléculaire
- 64 kDa
- ID gène
- 104884
- NCBI Accession
- NM_028354, NP_082630
-