TDP1 anticorps (C-Term)
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- Antigène Voir toutes TDP1 Anticorps
- TDP1 (Tyrosyl-DNA Phosphodiesterase 1 (TDP1))
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Épitope
- C-Term
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Reactivité
- Humain, Souris, Rat, Cheval, Boeuf (Vache), Cobaye, Chien, Lapin, Poisson zèbre (Danio rerio)
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp TDP1 est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- GRPPGKSAVP LHLIYPSVEN VRTSLEGYPA GGSLPYSIQT AEKQRWLHSY
- Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Zebrafish: 100%
- Attributs du produit
- This is a rabbit polyclonal antibody against Tdp1. It was validated on Western Blot.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the C-terminal region of mouse TDP1
- Top Product
- Discover our top product TDP1 Anticorps primaire
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- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeat freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- TDP1 (Tyrosyl-DNA Phosphodiesterase 1 (TDP1))
- Autre désignation
- Tdp1 (TDP1 Produits)
- Synonymes
- anticorps 2810481F14Rik, anticorps 4921509N21Rik, anticorps AI838772, anticorps AW493413, anticorps E430034L06Rik, anticorps MLZ-501, anticorps SCAN1, anticorps tdp1, anticorps MGC83708, anticorps TDP1, anticorps F8M21.60, anticorps F8M21_60, anticorps tyrosyl-DNA phosphodiesterase 1, anticorps tyrosyl-DNA phosphodiesterase 1, anticorps tyrosyl-DNA Phosphodiesterase (Tdp1), anticorps tyrosyl-DNA phosphodiesterase 1 L homeolog, anticorps tyrosyl-DNA phosphodiesterase-like protein, anticorps TDP1, anticorps Tc00.1047053511191.10, anticorps Tdp1, anticorps tdp1.L, anticorps tdp1, anticorps PTRG_11198, anticorps MCYG_02121, anticorps MGYG_03035
- Sujet
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The protein encoded by this gene is involved in repairing stalled topoisomerase I-DNA complexes by catalyzing the hydrolysis of the phosphodiester bond between the tyrosine residue of topoisomerase I and the 3-prime phosphate of DNA. This protein may also remove glycolate from single-stranded DNA containing 3-prime phosphoglycolate, suggesting a role in repair of free-radical mediated DNA double-strand breaks. This gene is a member of the phospholipase D family and contains two PLD phosphodiesterase domains. Mutations in this gene are associated with the disease spinocerebellar ataxia with axonal neuropathy (SCAN1). While several transcript variants may exist for this gene, the full-length natures of only two have been described to date. These two represent the major variants of this gene and encode the same isoform.
Protein Size: 609 - Poids moléculaire
- 66 kDa
- ID gène
- 55775
- NCBI Accession
- NM_001008744, NP_001008744
- UniProt
- Q9NUW8
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