GBA3 anticorps (N-Term)

N° du produit ABIN2787250

Détail du produit anti-GBA3 anticorps

Antigène: GBA3 (Glucosidase, Beta, Acid 3 (Cytosolic) (GBA3))

Épitope: N-Term

Reactivité: Humain, Rat, Chien, Cheval, Boeuf (Vache), Cobaye, Porc, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GBA3 est non-conjugé

Application: Western Blotting (WB)

Séquence: LTHYRFSLSW SRLLPDGTTG FINQKGIDYY NKIIDDLLKN GVTPIVTLYH

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Pig: 100%, Rabbit: 93%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against GBA3. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human GBA3

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 469 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur GBA3

Antigène: GBA3 (Glucosidase, Beta, Acid 3 (Cytosolic) (GBA3))

Autre désignation: GBA3 (GBA3 Produits)

Synonymes: anticorps im:6912508, anticorps CBG, anticorps CBGL1, anticorps GLUC, anticorps KLRP, anticorps glucosylceramidase beta 3, anticorps glucosidase, beta, acid 3 (gene/pseudogene), anticorps glucosidase, beta, acid 3 (cytosolic), anticorps cytosolic beta-glucosidase, anticorps glucosylceramidase beta 3 (gene/pseudogene), anticorps Gba3, anticorps gba3, anticorps GBA3, anticorps LOC100344458

Sujet: GBA3, or cytosolic beta-glucosidase (EC 3.2.1.21), is a predominantly liver enzyme that efficiently hydrolyzes beta-D-glucoside and beta-D-galactoside, but not any known physiologic beta-glycoside, suggesting that it may be involved in detoxification of plant glycosides (de Graaf et al., 2001 [PubMed 11389701]). GBA3 also has significant neutral glycosylceramidase activity (EC 3.2.1.62), suggesting that it may be involved in a nonlysosomal catabolic pathway of glucosylceramide metabolism (Hayashi et al., 2007 [PubMed 17595169]).
Alias Symbols: CBGL1, GLUC, KLrP, MGC104276, MGC126878
Protein Interaction Partner: PRKCSH, UBC,
Protein Size: 469

Poids moléculaire: 54 kDa

ID gène: 57733

NCBI Accession: NM_020973, NP_066024

UniProt: Q9H227