CARD9 anticorps (Middle Region)

N° du produit ABIN2787348

Détail du produit anti-CARD9 anticorps

Antigène: CARD9 (Caspase Recruitment Domain Family, Member 9 (CARD9))

Épitope: Middle Region

Reactivité: Humain, Souris, Cheval, Chien

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CARD9 est non-conjugé

Application: Western Blotting (WB)

Séquence: ALHQEQVLRN PHDAGLSSGE PPEKERRRLK ESFENYRRKR ALRKMQKGWR

Homologie: Dog: 92%, Horse: 86%, Human: 100%, Mouse: 90%

Attributs du produit: This is a rabbit polyclonal antibody against CARD9. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human CARD9

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 536 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur CARD9

Antigène: CARD9 (Caspase Recruitment Domain Family, Member 9 (CARD9))

Autre désignation: CARD9 (CARD9 Produits)

Synonymes: anticorps Gm782, anticorps card9, anticorps CANDF2, anticorps hCARD9, anticorps caspase recruitment domain family, member 9, anticorps caspase recruitment domain family member 9, anticorps Card9, anticorps CARD9, anticorps card9

Sujet: The protein encoded by this gene is a member of the CARD protein family, which is defined by the presence of a characteristic caspase-associated recruitment domain (CARD). CARD is a protein interaction domain known to participate in activation or suppression of CARD containing members of the caspase family, and thus plays an important regulatory role in cell apoptosis. This protein was identified by its selective association with the CARD domain of BCL10, a postive regulator of apoptosis and NF-kappaB activation, and is thought to function as a molecular scaffold for the assembly of a BCL10 signaling complex that activates NF-kappaB. Several alternatively spliced transcript variants have been observed, but their full-length nature is not clearly defined.
Alias Symbols: hCARD9, CANDF2
Protein Interaction Partner: KRTAP10-3, MFAP1, MEOX2, LMO1, ABLIM1, KRT31, KRT19, PHC2, DAXX, TRIM23, AES, KRTAP10-5, KRTAP10-1, CCDC36, TRIM42, CEP57L1, RTP5, PPP1R18, TCEANC, ALS2CR11, ZNF417, CWF19L2, ZNF572, KRT40, SSX2IP, PNMA5, C1orf94, ZNF587, LZTS2, ZCCHC7, FAM161A, CEP70, FA
Protein Size: 536

Poids moléculaire: 62 kDa

ID gène: 64170

NCBI Accession: NM_052813, NP_434700

UniProt: Q9H257

Pathways: Activation of Innate immune Response