RAD1 anticorps (Middle Region)

N° du produit ABIN2787356

Détail du produit anti-RAD1 anticorps

Antigène: RAD1 (Cell Cycle Checkpoint Protein RAD1 (RAD1))

Épitope: Middle Region

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye, Cheval, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RAD1 est non-conjugé

Application: Western Blotting (WB)

Séquence: ITMSPDKPYF RLSTFGNAGS SHLDYPKDSD LMEAFHCNQT QVNRYKISLL

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against RAD1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human RAD1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 282 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur RAD1

Antigène: RAD1 (Cell Cycle Checkpoint Protein RAD1 (RAD1))

Autre désignation: RAD1 (RAD1 Produits)

Synonymes: anticorps HRAD1, anticorps REC1, anticorps zgc:56502, anticorps zgc:77779, anticorps RAD1, anticorps xrad1, anticorps DKFZp459H1127, anticorps RAD1 checkpoint DNA exonuclease, anticorps RAD1 homolog (S. pombe), anticorps RAD1, anticorps Rad1, anticorps rad1

Sujet: This gene encodes a component of a heterotrimeric cell cycle checkpoint complex, known as the 9-1-1 complex, that is activated to stop cell cycle progression in response to DNA damage or incomplete DNA replication. The 9-1-1 complex is recruited by RAD17 to affected sites where it may attract specialized DNA polymerases and other DNA repair effectors. Alternatively spliced transcript variants of this gene have been described.
Alias Symbols: HRAD1, REC1
Protein Interaction Partner: ATRX, FEN1, UBC, MSH3, MSH2, MSH6, COPS5, HUS1, ATR, MAP1LC3B, HUS1B, RAD9B, RAD17, POLB, DNAJC7, PARK2, RPA2, RPA1, RAD9A,
Protein Size: 282

Poids moléculaire: 32 kDa

ID gène: 5810

NCBI Accession: NM_002853, NP_002844

UniProt: O60671

Pathways: M Phase