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ASAH1 anticorps (N-Term)

ASAH1 Reactivité: Humain, Souris, Rat, Chien, Boeuf (Vache), Cobaye, Cheval, Lapin WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2787375
  • Antigène Voir toutes ASAH1 Anticorps
    ASAH1 (N-Acylsphingosine Amidohydrolase (Acid Ceramidase) 1 (ASAH1))
    Épitope
    • 15
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivité
    • 29
    • 21
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Humain, Souris, Rat, Chien, Boeuf (Vache), Cobaye, Cheval, Lapin
    Hôte
    • 39
    • 5
    Lapin
    Clonalité
    • 39
    • 5
    Polyclonal
    Conjugué
    • 20
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp ASAH1 est non-conjugé
    Application
    • 33
    • 14
    • 13
    • 13
    • 10
    • 10
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB)
    Séquence
    MPGRSCVALV LLAAAVSCAV AQHAPPWTED CRKSTYPPSG PTYRGAVPWY
    Homologie
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 92%, Rat: 100%
    Attributs du produit
    This is a rabbit polyclonal antibody against ASAH1. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogène
    The immunogen is a synthetic peptide directed towards the N terminal region of human ASAH1
    Top Product
    Discover our top product ASAH1 Anticorps primaire
  • Indications d'application
    Optimal working dilutions should be determined experimentally by the investigator.
    Commentaires

    Antigen size: 395 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Tan, Liu, Fox, Barth, Sharma, Turner, Awwad, Dewey, Doi, Spitzer, Shah, Morad, Desai, Amin, Zhu, Liao, Yun, Kester, Claxton, Wang, Cabot, Schuchman, Levine, Feith, Loughran: "Acid ceramidase is upregulated in AML and represents a novel therapeutic target." dans: Oncotarget, Vol. 7, Issue 50, pp. 83208-83222, (2016) (PubMed).

    Elamin, Titz, Dijon, Merg, Geertz, Schneider, Martin, Schlage, Frentzel, Talamo, Phillips, Veljkovic, Ivanov, Vanscheeuwijck, Peitsch, Hoeng: "Quantitative proteomics analysis using 2D-PAGE to investigate the effects of cigarette smoke and aerosol of a prototypic modified risk tobacco product on the lung proteome in C57BL/6 mice." dans: Journal of proteomics, Vol. 145, pp. 237-45, (2016) (PubMed).

  • Antigène
    ASAH1 (N-Acylsphingosine Amidohydrolase (Acid Ceramidase) 1 (ASAH1))
    Autre désignation
    ASAH1 (ASAH1 Produits)
    Synonymes
    anticorps AC, anticorps ACDase, anticorps ASAH, anticorps PHP, anticorps PHP32, anticorps SMAPME, anticorps 2310081N20Rik, anticorps Asah, anticorps MGC82286, anticorps asah1, anticorps zgc:101637, anticorps ASAH1, anticorps zgc:66026, anticorps N-acylsphingosine amidohydrolase 1, anticorps N-acylsphingosine amidohydrolase (acid ceramidase) 1, anticorps N-acylsphingosine amidohydrolase (acid ceramidase) 1 L homeolog, anticorps N-acylsphingosine amidohydrolase (acid ceramidase) 1a, anticorps Acid ceramidase, anticorps N-acylsphingosine amidohydrolase (acid ceramidase) 1b, anticorps ASAH1, anticorps Asah1, anticorps asah1.L, anticorps asah1a, anticorps asah-1, anticorps asah1b
    Sujet
    This gene encodes a heterodimeric protein consisting of a nonglycosylated alpha subunit and a glycosylated beta subunit that is cleaved to the mature enzyme posttranslationally. The encoded protein catalyzes the synthesis and degradation of ceramide into
    Alias Symbols: AC, ASAH, FLJ21558, FLJ22079, PHP, PHP32, ACDase
    Protein Interaction Partner: SRPK1, CAMK1D, FBXO6, UBC, PSMA3, Bub1b, TSC22D1, SETDB1, SMPD1,
    Protein Size: 395
    Poids moléculaire
    44 kDa
    ID gène
    427
    NCBI Accession
    NM_177924, NP_808592
    UniProt
    Q13510
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