UBE2K anticorps (Middle Region)
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- Antigène Voir toutes UBE2K Anticorps
- UBE2K (Ubiquitin-Conjugating Enzyme E2K (UBE2K))
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Épitope
- Middle Region
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Reactivité
- Humain, Souris, Rat, Poisson zèbre (Danio rerio), Chien, Boeuf (Vache), Cheval, Lapin, Chévre, Cobaye
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp UBE2K est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- TVLLSLQALL AAAEPDDPQD AVVANQYKQN PEMFKQTARL WAHVYAGAPV
- Homologie
- Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
- Attributs du produit
- This is a rabbit polyclonal antibody against UBE2K. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the middle region of human UBE2K
- Top Product
- Discover our top product UBE2K Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 200 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- UBE2K (Ubiquitin-Conjugating Enzyme E2K (UBE2K))
- Autre désignation
- UBE2K (UBE2K Produits)
- Synonymes
- anticorps E2-25K, anticorps HIP2, anticorps HYPG, anticorps LIG, anticorps UBC1, anticorps E2-25k, anticorps Hip2, anticorps Hypg, anticorps Lig, anticorps e2-25k, anticorps hip2, anticorps hypg, anticorps lig, anticorps AW492011, anticorps D5Ertd601e, anticorps ube2k, anticorps zgc:103472, anticorps zgc:110791, anticorps ubiquitin conjugating enzyme E2 K, anticorps ubiquitin-conjugating enzyme E2K, anticorps ubiquitin conjugating enzyme E2 K S homeolog, anticorps ubiquitin-conjugating enzyme E2Kb (UBC1 homolog, yeast), anticorps ubiquitin-conjugating enzyme E2Ka (UBC1 homolog, yeast), anticorps UBE2K, anticorps Ube2k, anticorps ube2k.S, anticorps ube2k, anticorps ube2kb, anticorps ube2ka
- Sujet
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UBE2K belongs to the ubiquitin-conjugating enzyme family. This protein interacts with RING finger proteins, and it can ubiquitinate huntingtin, the gene product for Huntington's disease. Known functions for this protein include a role in aggregate formation of expanded polyglutamine proteins and the suppression of apoptosis in polyglutamine diseases, a role in the dislocation of newly synthesized MHC class I heavy chains from the endoplasmic reticulum, and involvement in foam cell formation. The protein encoded by this gene belongs to the ubiquitin-conjugating enzyme family. This protein interacts with RING finger proteins, and it can ubiquitinate huntingtin, the gene product for Huntington's disease. Known functions for this protein include a role in aggregate formation of expanded polyglutamine proteins and the suppression of apoptosis in polyglutamine diseases, a role in the dislocation of newly synthesized MHC class I heavy chains from the endoplasmic reticulum, and involvement in foam cell formation. Multiple transcript variants encoding different isoforms have been identified for this gene.
Alias Symbols: DKFZp564C1216, DKFZp686J24237, E2-25K, HIP2, HYPG, LIG, UBC1
Protein Interaction Partner: DDI1, DTX3, MIPOL1, TRIM39, ANAPC11, RNF138, SIAH1, RNF5, REL, FZR1, UBC, UBA1, MARCH7, AMFR, TP53, MDM2, BAG3, PRRG4, IQCB1, HTT, CDC6, WDR1, TYMS, TXN, TXNDC17, WDR61, ITCH, NEDD4L, WWP2, NXF1, NUB1, PIAS4, CASP12, SUMO1, SUMO2, DIABLO, UBE2I, CCNB1, BR
Protein Size: 200 - Poids moléculaire
- 22 kDa
- ID gène
- 3093
- NCBI Accession
- NM_005339, NP_005330
- UniProt
- P61086
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