PSMD4/ASF anticorps (N-Term)
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- Antigène Voir toutes PSMD4/ASF (Psmd4) Anticorps
- PSMD4/ASF (Psmd4) (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 4 (Psmd4))
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Épitope
- N-Term
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Reactivité
- Humain, Souris, Rat, Boeuf (Vache), Mouton, Chien, Lapin, Cobaye, Cheval, Poisson zèbre (Danio rerio), Saccharomyces cerevisiae
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp PSMD4/ASF est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- VLESTMVCVD NSEYMRNGDF LPTRLQAQQD AVNIVCHSKT RSNPENNVGL
- Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Yeast: 92%, Zebrafish: 100%
- Attributs du produit
- This is a rabbit polyclonal antibody against PSMD4. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the N terminal region of human PSMD4
- Top Product
- Discover our top product Psmd4 Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 377 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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Age-related modifications of egr1 expression and ubiquitin-proteasome components in pet dog hippocampus." dans: Mechanisms of ageing and development, Vol. 130, Issue 5, pp. 320-7, (2009) (PubMed).
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Age-related modifications of egr1 expression and ubiquitin-proteasome components in pet dog hippocampus." dans: Mechanisms of ageing and development, Vol. 130, Issue 5, pp. 320-7, (2009) (PubMed).
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- Antigène
- PSMD4/ASF (Psmd4) (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 4 (Psmd4))
- Autre désignation
- PSMD4 (Psmd4 Produits)
- Synonymes
- anticorps af-1, anticorps mcb1, anticorps pub-r5, anticorps rpn10, anticorps PSMD4, anticorps DDBDRAFT_0202512, anticorps DDBDRAFT_0232981, anticorps DDB_0202512, anticorps DDB_0232981, anticorps AF, anticorps AF-1, anticorps ASF, anticorps MCB1, anticorps Rpn10, anticorps S5A, anticorps pUB-R5, anticorps xrpn10c, anticorps Af1, anticorps Mcb1, anticorps angiocidin, anticorps im:6912672, anticorps psmd4, anticorps wu:fc68c04, anticorps zgc:110247, anticorps proteasome 26S subunit, non-ATPase 4, anticorps 26S proteasome non-ATPase regulatory subunit 4, anticorps 26s proteasome non-atpase regulatory subunit 4 (26s proteasomeregulatory subunit s5a), anticorps proteasome 26S subunit, non-ATPase 4 L homeolog, anticorps proteasome (prosome, macropain) 26S subunit, non-ATPase, 4, anticorps proteasome 26S subunit, non-ATPase 4b, anticorps psmd4, anticorps PSMD4, anticorps LOC100194679, anticorps psmD4, anticorps LOC100283637, anticorps Smp_000740.1, anticorps psmd4.L, anticorps Psmd4, anticorps psmd4b
- Sujet
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The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. PSMD4 encodes one of the non-ATPase subunits of the 19S regulator lid. The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the non-ATPase subunits of the 19S regulator lid. Pseudogenes have been identified on chromosomes 10 and 21. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: AF, AF-1, ASF, MCB1, Rpn10, S5A, pUB-R5
Protein Interaction Partner: UBC, cdc20, XPC, SPRTN, PSMD14, MDM2, PSMC2, PSMA1, ADRM1, UBQLN1, TXNL1, PSMD3, PSMD2, PSMD1, PSMC6, PSMC4, PSMC1, UCHL5, RPS12, PSMD8, UBQLN4, VCP, GJA1, DIO2, SCHIP1, FBXO6, PARK2, UL76, FBXO25, LOC100044627, Gm4705, LOC677113, Rps6-ps4, Rpl34-ps1, Rpl
Protein Size: 377 - Poids moléculaire
- 41 kDa
- ID gène
- 5710
- NCBI Accession
- NM_002810, NP_002801
- UniProt
- P55036
- Pathways
- Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA, Ubiquitin Proteasome Pathway
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